Merck & Co., Inc
Volume 127 · 127 F.T.C. 156
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Complaint 127 F.T.C.
IN THE MATTER OF
MERCK & CO., INC., ET AL.
CONSENT ORDER, ETC., IN REGARD TO ALLEGED VIOLATION OF SEC. 7 OF THE CLAYTON ACT AND SEC. 5 OF THE FEDERAL TRADE COMMISSION ACT
Docket C-3853. Complaint, Feb. 18, 1999--Decision, Feb. 18, 1999
This consent order, among other things, requires Merck & Co., Inc., a leading pharmaceutical manufacturer, and its subsidiary to maintain and make available an open formulary, containing information concerning the relative costs of drugs, and the respondents shall appoint or reappoint an independent committee with the authority to maintain an open formulary. In addition, the consent order prohibits Merck and Medco from sharing proprietary or other non-public information.
Participants
For the Commission: Karen Berg, Veronica Kayne, Michael McNeely, Naomi Licker, Roberta Baruch, Willard Tom, William Baer, Charissa Wellford, J. Elizabeth Callison, Leslie Farber and Geary Gessler.
For the respondents: Michael Sohn, Arnold & Porter, Washington, D.C.
COMPLAINT
The Federal Trade Commission, having reason to believe that respondent Merck & Co., Inc. ("Merck"), a corporation subject to the jurisdiction of the Commission, acquired Medco Containment Services, Inc., a corporation, now respondent Merck-Medco Managed Care, L.L.C. ("Medco"), a limited liability company subject to the jurisdiction of the Commission, that such acquisition violates Section 5 of the Federal Trade Commission Act, as amended, 15 U.S.C. 45, and Section 7 of the Clayton Act, as amended, 15 U.S.C. 18, and that a proceeding by it in respect thereof would be in the public interest, hereby issues its complaint pursuant to Section 11 of the Clayton Act, 15 U.S.C. 21, and Section 5(b) of the Federal Trade Commission Act, as amended, 15 U.S.C. 45, stating its charges as follows:
PARAGRAPH 1. Respondent Merck & Co., Inc., is a corporation organized, existing and doing business under and by virtue of the laws of the State of New Jersey, with its principal office located at One Merck Drive, Whitehouse Station, New Jersey.
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PAR. 2. Respondent Merck is engaged in the development, production and sale of pharmaceutical products, including Mevacor and Zocor, which are "HMG-CoA reductase inhibitors" used for the treatment of high cholesterol, and Prinivil and Vasotec, which are "angiotensin converting enzyme inhibitors" ("ACE Inhibitors") used for the treatment of hypertension, high blood pressure, and heart disease.
PAR. 3. Respondent Merck-Medco Managed Care, L.L.C., is a limited liability company organized, existing and doing business under and by virtue of the laws of the State of Delaware, with its principal office located at 100 Summit Avenue, Montvale, New Jersey.
PAR. 4. Respondent Medco provides pharmacy benefit management ("PBM") services to corporations, insurance companies, labor unions, Blue Cross Blue Shield organizations, federal and state employee plans, health maintenance organizations, and other members of the healthcare industry.
PAR. 5. On November 18, 1993, Merck acquired all the outstanding stock of Medco Containment Services, Inc., now doing business as Merck-Medco Managed Care, L.L.C., for approximately $6.6 billion.
PAR. 6. At all times relevant herein, respondents Merck and Medco have been, and are now, engaged in commerce as "commerce" is defined in Section 1 of the Clayton Act, as amended, 15 U.S.C. 12, and are "corporations" whose businesses are in or affecting commerce as "corporation" and "commerce" are defined in Section 4 of the Federal Trade Commission Act, as amended, 15 U.S.C. 44.
PAR. 7. A relevant line of commerce within which to analyze the effects of this acquisition is the provision of pharmacy benefit management ("PBM") services by national full-service PBM firms, and any narrower markets contained therein. Other relevant lines of commerce within which to analyze the effects of this acquisition are the development, manufacture and sale of pharmaceutical products in specific therapeutic categories, and narrower markets contained therein (including, but not limited to, the markets for HMG-CoA reductase inhibitors and angiotensin converting enzyme inhibitors).
PAR. 8. A relevant section of the country within which to analyze the effects of this acquisition is the United States.
Complaint 127 F.T.C.
PAR. 9. The relevant market for PBM services by national full-service PBM firms, and the relevant markets for pharmaceutical products in specific therapeutic categories, are moderately to highly concentrated.
PAR. 10. There are substantial entry barriers into the relevant markets. Even if new entry were to occur, it would take a long time, during which time substantial harm to competition could occur.
PAR. 11. As part of its PBM services, Medco maintains drug formularies, which are listings, by therapeutic category, of ambulatory drug products that are approved for use by the U.S. Food & Drug Administration, and which are used by pharmacies, physicians, third-party payors, and other persons, to guide in the prescribing and dispensing of pharmaceuticals. Merck pharmaceutical products are included on Medco's formularies. Medco also provides other PBM services, including claims processing, drug utilization review, pharmacy network administration, mail service, and related services. Medco negotiates with pharmaceutical manufacturers, including Merck, concerning placement of drugs on Medco's formularies, rebates, discounts, prices to be paid for pharmaceutical products purchased pursuant to pharmacy benefit plans managed by Medco, and similar matters. Medco thereby influences the prices of pharmaceutical products and the availability of such products under the Medco pharmacy benefit plans.
PAR. 12. The effects of Merck's acquisition of Medco may be substantially to lessen competition in the relevant markets in violation of Section 7 of the Clayton Act, as amended, 15 U.S.C. 18, and Section 5 of the Federal Trade Commission Act, as amended, 15 U.S.C. 45, in the following ways, among others:
(a) Products of manufacturers other than Merck are likely to be foreclosed from Medco's formularies; (b) Reciprocal dealing, coordinated interaction, interdependent conduct, and tacit collusion among Merck and other vertically integrated pharmaceutical companies will be enhanced; (c) Medco will be eliminated as an independent negotiator of pharmaceutical prices with manufacturers; (d) Incentives of other manufacturers to develop innovative pharmaceuticals will be diminished; and
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(e) Pharmaceutical prices are likely to increase and the quality of the pharmaceuticals available to consumers is likely to diminish.
PAR. 13. Merck's acquisition of Medco violates Section 7 of the Clayton Act, as amended, 15 U.S.C. 18, and Section 5 of the Federal Trade Commission Act, as amended, 15 U.S.C. 45.
DECISION AND ORDER
The Federal Trade Commission ("Commission") having initiated an investigation of the acquisition by respondent Merck and Company, Inc., of respondent Merck-Medco Managed Care, LLC, and the respondents having been furnished thereafter with a copy of a draft of complaint which the Bureau of Competition proposed to present to the Commission for its consideration and which, if issued by the Commission, would charge respondents with a violation of Section 5 of the Federal Trade Commission Act, as amended, 15 U.S.C. 45, and a violation of Section 7 of the Clayton Act, as amended, 15 U.S.C. 18; and
The respondents, their attorneys, and counsel for the Commission having thereafter executed an agreement containing a consent order, an admission by the respondents of all the jurisdictional facts set forth in the aforesaid draft of complaint, a statement that the signing of said agreement is for settlement purposes only and does not constitute an admission by respondents that the law has been violated as alleged in such complaint, or that the facts as alleged in such complaint, other than jurisdictional facts, are true and waivers and other provisions as required by the Commission's Rules; and
The Commission having thereafter considered the matter and having determined that it had reason to believe that the respondents have violated the said Acts, and that a complaint should issue stating its charges in that respect, and having thereupon accepted the executed consent agreement and placed such agreement on the public record for a period of sixty (60) days, and having duly considered the comments received, now in further conformity with the procedure prescribed in Section 2.34 of its Rules, the Commission hereby issues its complaint, makes the following jurisdictional findings and enters the following order:
Decision and Order 127 F.T.C.
1. Respondent Merck & Company, Inc., ("Merck") is a corporation organized, existing and doing business under and by virtue of the laws of the State of New Jersey, with its office and principal place of business located at One Merck Drive, Whitehouse Station, New Jersey. 2. Respondent Merck-Medco Managed Care, LLC, ("Medco") is a limited liability company organized, existing and doing business under and by virtue of the laws of the State of Delaware, with its office and principal place of business located at 100 Summit Avenue, Montvale, New Jersey. 3. The Federal Trade Commission has jurisdiction of the subject matter of this proceeding and of the respondents, and the proceeding is in the public interest.
ORDER
I.
It is ordered, That the following definitions shall apply herein:
A. "Merck" means Merck & Co., Inc., its directors, officers, employees, agents, representatives, predecessors, successors and assigns; its subsidiaries, divisions, groups, affiliates, partnerships and joint ventures controlled by Merck & Co., Inc., other than Medco or any other supplier of PBM Services owned or controlled by Merck; and the respective directors, officers, employees, agents, representatives, successors and assigns of each. B. "Medco" means Merck-Medco Managed Care, L.L.C., its managers, directors, officers, employees, agents, representatives, predecessors, successors and assigns; its subsidiaries, divisions, groups, affiliates, partnerships and joint ventures controlled by Medco other than Merck; all other suppliers of PBM Services owned or controlled by Merck; and the respective directors, officers, employees, agents, representatives, successors and assigns of each. C. "Respondents" means both Merck and Medco. D. "Commission" means the Federal Trade Commission. E. "Formulary" means a listing, by therapeutic category, of branded and generic ambulatory drug products that are approved for use by the U.S. Food & Drug Administration ("FDA"), which listing is made available to pharmacies, physicians, third-party payors, or other persons involved in the healthcare industry, to guide in the prescribing or dispensing of pharmaceuticals. An "Open Formulary"
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is a formulary that allows the inclusion of any ambulatory prescription drug product approved by the FDA for use in the United States, which the P&T Committee (defined below) determines is appropriate for inclusion in such formulary. For purposes of this order, an Open Formulary may provide truthful information stating or indicating the benefits of drugs on the formulary. F. "Pharmacy Benefit Management Services" or "PBM Services" means services provided by a pharmacy benefits manager, such as formulary services, negotiation of rebates or discounts from pharmaceutical manufacturers, prescription claims processing, and drug utilization review.
G. "Formulary Services" means the provision, development, establishment, management or maintenance of a formulary by a pharmacy benefits manager. For purposes of this order, "management" of a formulary includes the negotiation and administration of rebate or discount agreements with pharmaceutical manufacturers for drugs included on a formulary. H. "Merck Non-Public Information" means information not in the public domain that is provided to Merck by a supplier of PBM Services in connection with the supply of PBM Services and that directly or indirectly discloses actual, relative or proposed prices, discounts, rebates, other trade terms (including, but not limited to, returned goods arrangements, delivery arrangements, performance levels and guarantees) or similar terms or conditions of sale of such supplier of PBM Services.
I. "Medco Non-Public Information" means information not in the public domain that is provided to Medco by a manufacturer of prescription drug products in connection with the supply of prescription drug products and that directly or indirectly discloses actual, relative or proposed prices, discounts, rebates, other trade terms (including, but not limited to, returned goods arrangements, delivery arrangements, and payment terms or schedules) or similar terms or conditions of sale of such manufacturer of prescription drug products. J. "Auditors" means 1) those employees of Merck whose primary responsibility is systematically inspecting, substantiating, and reporting on: the reliability and integrity of Merck's information; its compliance with laws and regulations; the safeguarding of its assets; the economical and efficient use of its resources; and the accomplishment of its established objectives and goals; and who regularly work
Decision and Order 127 F.T.C.
in the organizational subdivision of Merck with company-wide responsibility for performing these functions, and 2) employees of independent firms retained by Merck to perform one or more of these functions.
K. "Pharmacy and Therapeutics Committee" or "P&T Committee" means a group of healthcare professionals, such as doctors, pharmacists, and pharmacologists, appointed for the purpose of evaluating prescription drug products for inclusion on a formulary.
II.
It is ordered, That:
A. Within sixty (60) days from the date this order becomes final, Merck shall cause Medco to, and Medco shall, maintain, disclose the availability of, and make available an Open Formulary. Such Open Formulary shall provide information concerning the relative costs of drugs listed on such formulary and such information shall be truthful and accurate. As of the date this order becomes final, the Medco "Universal Formulary," a copy of which is attached hereto as Appendix A, shall be deemed an Open Formulary that complies with this paragraph II.A.
B. Within thirty (30) days from the date this order becomes final, Merck shall cause Medco to, and Medco shall, appoint or reappoint an independent P&T Committee with the authority and responsibility to maintain an Open Formulary as required by paragraph II.A above. Such P&T Committee shall make all decisions concerning the inclusion of drugs on such Open Formulary, the exclusion of drugs from such Open Formulary, and the clinical and therapeutic advice and evaluation appearing in such Open Formulary, and shall operate according to the following provisions:
1. Such P&T Committee shall consist of at least seven (7) members, all of whom shall be physicians, pharmacists, pharmacologists, or other healthcare professionals.
2. A majority of the P&T Committee shall consist of persons who are not employees, officers, directors, or agents of, and who have no financial interest in: (a) Merck, (b) Medco, or (c) any other person who has an ownership interest in Merck or Medco; provided, however, that Medco may pay P&T Committee members reasonable and customary consulting fees and/or honoraria for their services.
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Any person who meets the criteria set forth in this subparagraph shall be deemed an "independent" member of the P&T Committee. 3. Each independent member of the P&T Committee shall have one vote on each decision of the P&T Committee. 4. All members of the P&T Committee who are employees, officers, directors, or agents of, or who have a financial interest in, Merck, Medco, or any other person who has an ownership interest in Merck or Medco, shall not be entitled to vote on decisions of the P&T Committee.
5. All independent members of the P&T Committee shall be appointed for two-year terms, except that the initial terms for approximately one-half of the independent members may be for fewer than two years if necessary to ensure that approximately one-half of the independent members' terms expire each year. At the expiration of their terms, or upon the occurrence of a vacancy, members may be reappointed, or new members may be appointed, by a majority of the then-appointed independent members of the P&T Committee. 6. No independent member of the P&T Committee may be removed except for cause by vote of a majority of the independent members of the P&T Committee. 7. In performing its responsibilities in maintaining the Open Formulary, the P&T Committee shall utilize only criteria relating to safety, efficacy, FDA approved indications, side effects, contraindications, pharmacokinetics, patient compliance, physician follow-up requirements, effect on emergency room visits and hospitalizations, laboratory tests, cost, and similar objective factors. Such P&T Committee shall give no preference to the products of Merck, or of any other person with an ownership interest in Medco, except on the basis of such objective criteria. 8. Merck shall cause Medco to, and Medco shall, cover the reasonable costs and expenses of the P&T Committee, and Merck shall cause Medco to, and Medco shall, indemnify the P&T Committee against any losses or claims of any kind that might arise out of its performance of functions under this order, except to the extent that such losses or claims result from misfeasance, gross negligence, willful or wanton acts, or bad faith. 9. Medco shall maintain written records, for five (5) years from the date thereof, sufficient to show the basis and rationale for all P&T
Decision and Order 127 F.T.C.
Committee decisions relating to the exclusion of any products from the Open Formulary required by paragraph II.A.
C. Merck shall cause Medco to, and Medco shall, accept all discounts, rebates or other concessions offered solely in connection with the Open Formulary by any manufacturer, seller or distributor of pharmaceutical products included by the P&T Committee on the Open Formulary, and Merck shall cause Medco to, and Medco shall, ensure that all such discounts, rebates, or concessions are truthfully and accurately reflected in the information concerning the relative costs of drugs listed on such Open Formulary.
D. Nothing in this order shall preclude Medco from offering any formulary other than the Open Formulary to any customer.
E. Merck shall cause Medco to, and Medco shall, provide a copy of this order to each member of the P&T Committee on or before the date of each such person's appointment to such P&T Committee or on or before the date this order becomes final.
III.
It is further ordered, That:
A. Merck shall not provide, disclose, or otherwise make available to Medco any Merck Non-Public Information; and
B. Medco shall not provide, disclose, or otherwise make available to Merck any Medco Non-Public Information; provided, however:
1. For the purpose of obtaining legal advice, Medco may provide Medco Non-Public Information to lawyers for Merck, on condition that such lawyers for Merck shall not disclose such Medco Non-Public Information to any other person at Merck not expressly permitted to receive the information under this Section III.B. and shall not use such information for any purpose other than providing legal advice;
2. For the purpose of obtaining legal advice, Merck may provide Merck Non-Public Information to lawyers for Medco, on condition that such lawyers for Medco shall not disclose such Merck Non-Public Information to any other person at Medco not expressly permitted to receive the information under this Section III.B. and shall not use such information for any purpose other than providing legal advice; and
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3. Medco may disclose to Merck auditors Medco Non-Public Information to the extent necessary to enable Merck auditors to perform their auditing duties in the ordinary course of business, on condition that such auditors shall not use such Non-Public Information for any other purpose and shall not disclose such Non-Public Information to any other person at Merck not expressly permitted to receive the information under this Section III.B.
IV.
It is further ordered, That Merck shall retain all documents and shall cause Medco to separately retain all documents, and Medco shall retain all documents, that relate to (A) the exclusion of any prescription drug product from the Open Formulary required by paragraph II.A above, (B) any preference or ranking accorded to any prescription drug product on the Open Formulary required by paragraph II.A above, or (C) statements or indications of discounts, rebates, or other concessions, as described in paragraph II.C above, for a period of five (5) years from the date such document is created or received.
V.
It is further ordered, That Merck and Medco shall disclose the availability of the Open Formulary as follows:
A. Merck shall cause Medco to, and Medco shall, disclose the availability of the Open Formulary to all persons who currently have an agreement with Medco concerning PBM Services or concerning the inclusion of pharmaceuticals on a formulary, by providing to each such person a written communication containing the following statement not later than ten (10) days after initiation of contact between Medco and such person regarding renewal or extension of such person's existing agreement with Medco:
Medco maintains an Open Formulary that allows, subject to the determination of an independent Pharmacy and Therapeutics Committee, the inclusion of any ambulatory prescription drug product approved by the FDA for use in the United States. This Open Formulary will be provided to you upon request.
Decision and Order 127 F.T.C.
B. For a period of five (5) years from the date this order becomes final, Merck shall cause Medco to, and Medco shall, provide in writing the statement set forth in paragraph V.A above to each prospective customer of Medco at the time of Medco's response to such prospective customer's request for proposal, or at the time of Medco's initial written formulary proposal to such prospective customer, whichever occurs first.
VI.
It is further ordered, That respondents shall notify the Commission at least thirty (30) days prior to any proposed change in the corporate respondents such as dissolution, assignment, sale resulting in the emergence of a successor corporation, or the creation or dissolution of subsidiaries or any other change in the corporation that may affect compliance obligations arising out of the order.
VII.
It is further ordered, That:
A. Within thirty (30) days after the date this order becomes final, respondents shall submit to the Commission verified written reports setting forth in detail the manner and form in which they have complied and are complying with paragraph II.B of this order.
B. Within sixty (60) days after the date this order becomes final, respondents shall submit to the Commission verified written reports setting forth in detail the manner and form in which they have complied and are complying with paragraph II.A of this order.
C. One (1) year from the date this order becomes final, annually thereafter on the anniversary of the date this order becomes final until the order terminates, and at other times as the Commission may require, respondents shall file verified written reports with the Commission setting forth in detail the manner and form in which they have complied and are complying with this order.
D. Respondents shall include in their compliance reports a copy of the Open Formulary required by paragraph II.A above, and all written communications, internal memoranda, and reports and recommendations concerning compliance with the order.
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VIII.
It is further ordered, That, for the purpose of determining or securing compliance with this order, respondents shall permit any duly authorized representative of the Commission:
A. Access, during office hours and in the presence of counsel, to inspect and copy all books, ledgers, accounts, correspondence, memoranda and other records and documents in the possession or under the control of respondents relating to any matters contained in this order; and
B. Upon five days' notice to respondents and without restraint or interference from them, to interview officers, directors, or employees of respondents in the presence of counsel.
IX.
It is further ordered, That this order shall terminate on February 18, 2006.
Decision and Order 127 F.T.C. APPENDIX A
Merck-Medco Universal Formulary™
An[illegible]fectives Cardiovascular Endocrine G. I.
Psychotherapeutics R[illegible]ry S[illegible]
R Rx NAME GROUP NO
ATTACHMENT A
Merck-Medco Managed Care, L.L.C.
A subsidiary of Merck & Co., Inc.
MERCK & CO., INC., ET AL.
Decision and Order
APPENDIX A
Dear Provider,
The Universal Formulary is a list of selected FDA approved, prescription medications developed by Merck-Medco Managed Care's Pharmacy and Therapeutics (P&T) Committee. In a totally coordinated prescription drug benefit program, the formulary can assist you in maintaining quality of care and cost containment for your patient's benefit plan.
Our P&T Committee is an independent group of distinguished health care professionals with various medical and pharmacological specialties. The P&T Committee reviews drugs in all therapeutic categories and evaluates them on such objective criteria as safety and efficacy. To ensure the integrity of the formulary for our plan sponsors and their members, the P&T Committee reviews new and existing drugs on a regular basis and revises the formulary accordingly.
The Universal Formulary also includes specific information on the use of medications in the elderly that has been reviewed by an outside panel of geriatric experts. This information indicates those drugs that, in general, should not be prescribed to the elderly because they pose unnecessary risk. The Universal Formulary also provides information on drugs where the initial dosage should be decreased in the elderly.
Providers, as important professional resources in the coordinated managed care process, are invited to offer suggestions for the improvement of the Universal Formulary. Please send correspondence to Merck-Medco Managed Care, L.L.C., Clinical Services Department, 100 Summit Avenue, Montvale, New Jersey 07645.
Thank you for your continued support.
© Copyright 1998; Merck-Medco Managed Care, L.L.C.; PAID Prescriptions, L.L.C.; and Merck-Medco Rx Services pharmacies are subsidiaries of Merck & Co., Inc.
Decision and Order 127 F.T.C.
APPENDIX A
THERAPEUTIC CHAPTERS
1. Anti-Infectives 1.1 Penicillins 1.2 Tetracyclines 1.3 Cephalosporins 1.3.1 First Generation Cephalosporins 1.3.2 Second Generation Cephalosporins 1.3.3 Third Generation Cephalosporins 1.3.4 Carbacephems 1.4 Erythromycins & Other Macrolides 1.5 Quinolones 1.6 Sulfas and Related Agents 1.7 Urinary Tract Agents 1.8 Antivirals 1.8.1 Miscellaneous Antivirals 1.8.2 HIV/AIDS Therapy 1.9 Antifungal Agents 1.10 Vancomycin 1.11 Miscellaneous Anti-infectives 1.11.1 Miscellaneous Anti-infectives 1.11.2 Antiparasitics 1.11.3 Antimalarials 1.11.4 Antimycobacterials - 1.11.5 Aminoglycosides 2. Antineoplastics & Immunosuppressant Drugs 2.1 Antineoplastics & Immunosuppressant Drugs 2.1.1 Alkylating Agents 2.1.2 Antimetabolites 2.1.3 Androgens, Estrogens, Hormones & Related Drugs 2.1.3.1 Androgens 2.1.3.2 Estrogens 2.1.3.3 Hormones 2.1.3.4 Antiestrogens 2.1.3.5 Antiandrogens 2.1.5 Immunosuppressant Drugs 2.1.6 Miscellaneous Antineoplastic Drugs 2.2 Adjunctive Agents 2.2.1 Adjunctive Agents 3. Autonomic & CNS Drugs, Neurology & Psych 3.1 Narcotic Analgesics 3.1.1 Narcotics 3.1.2 Combination Narcotic/Analgesics 3.2 Propoxyphene 3.3 Non-Narcotic Analgesics 3.3.1 NSAIDs 3.3.2 Salicylates 3.3.3 Miscellaneous Analgesics 3.3.4 Narcotic Antagonists 3.4 Migraine & Cluster Headache Therapy 3.4.1 Headache Therapy 3.4.2 Antivertigo & Antiemetic Drugs 3.5 Antiparkinsonism Agents 3.6 Anticonvulsants 3.7 Miscellaneous Neurological Therapy 3.8 Muscle Relaxants & Antispasmodic Therapy 3.8.1 Muscle Relaxants & Antispasmodic Agents 3.8.2 Myasthenia Gravis 3.9 Psychotherapeutic Drugs 3.9.1 Hypnotic Agents 3.9.2 Antidepressant Agents 3.9.2.1 Tricyclics 3.9.2.2 Miscellaneous Antidepressants 3.9.2.3 MAO Inhibitors 3.9.2.4 Selective Serotonin Reuptake Inhibitors 3.9.3 Antipsychotics 3.9.3.1 Phenothiazines 3.9.3.2 Butyrophenones 3.9.3.3 Miscellaneous Antipsychotics 3.9.4 Miscellaneous Psychotherapeutic Agents 3.9.5 Anxiolytics 3.9.6 Barbiturates 4. Cardiovascular, Hypertension & Lipids 4.1 Antiarrhythmic Agents 4.2 Cardiac Glycosides 4.3 Nitrates 4.3.1 Rapid Acting Nitrates 4.3.2 Long Acting Nitrates 4.4 Coagulation Therapy 4.4.1 Anticoagulants 4.4.2 Antiplatelet Drugs 4.4.3 Heparin 4.4.4 Vitamin K 4.4.5 Hemostatics 4.4.6 Miscellaneous Coagulation Agents 4.5 Antihypertensive Therapy 4.5.1 Thiazide & Related Diuretics 4.5.2 Beta Blockers 4.5.3 Calcium Channel Blockers 4.5.4 ACE Inhibitors 4.5.5 Adrenergic Antagonists & Related Drugs 4.5.6 Agents for Pheochromocytoma 4.5.7 Vasodilators 4.5.8 Other Antihypertensive Combinations 4.5.9 Angiotensin II Receptor Blockers 4.6 Lipid/Cholesterol Lowering Agents 5. Dermatologicals/Topical Therapy 5.1 Topical Corticosteroids 5.1.1 Topical Corticosteroids Group I 5.1.2 Topical Corticosteroids Group II 5.1.3 Topical Corticosteroids Group III 5.1.4 Topical Corticosteroids Group IV 5.1.5 Topical Corticosteroids Group V 5.1.6 Topical Corticosteroids Group VI 5.1.7 Topical Corticosteroids Group VII 5.2 Topical Anesthetics 5.3 Therapy for Acne 5.4 Topical Antibacterials 5.5 Topical Antifungals 5.6 Topical Antivirals 5.7 Burn Therapy 5.8 Topical Enzymes 5.9 Keratolytics 5.10 Antipsoriatic/Antiseborrheic 5.11 Topical Scabicides/Pediculicides 5.12 Miscellaneous Dermatologicals 6. Ear, Nose & Throat Medications 6.1 Intranasal Steroids 6.2 Miscellaneous Otic Preparations 6.3 Otic Steroids/Antibiotics 6.4 Miscellaneous Agents
MERCK & CO., INC., ET AL.
Decision and Order APPENDIX A
7. Endocrine/Diabetes 7.1 Antithyroid Agents 7.2 Thyroid Hormones 7.3 Adrenal Hormones 7.4 Miscellaneous Hormones 7.4.1 Androgens 7.4.2 Ovulatory Stimulants 7.4.3 Miscellaneous Agents 7.4.4 Gonadotropin & Related Agents 7.5 Diabetes Therapy 7.5.1 Insulin Therapy 7.5.2 Oral Hypoglycemic Agents 7.5.3 Glucose Elevating Agents 7.5.4 Insulin Syringes 7.5.5 Blood Glucose Monitoring Strips 7.5.6 Blood Glucose Monitoring Meters 8. Gastroenterology 8.1 Ulcer Therapy 8.1.1 H2 Antagonists 8.1.2 Prostaglandins 8.1.3 Other Ulcer Therapy 8.1.4 Proton Pump Inhibitors 8.2 Antidiarrheals & Antispasmodics 8.2.1 Antidiarrheals 8.2.2 Antispasmodics 8.2.3 Combination Anticholinergics 8.3 Miscellaneous Gastrointestinal Agents 8.3.1 Bile Acids 8.3.2 Digestive Enzymes 8.3.3 Miscellaneous Gastrointestinal Agents 8.3.4 Antiemetics 8.3.5 Bowel Evacuants 9. Biotechnology Drugs 9.1.1 Erythroid Stimulants 9.1.2 Myeloid Stimulants 9.1.3 Interferons 9.1.4 Growth Hormones 10. Musculoskeletal & Rheumatology 10.1 NSAIDs 10.1.2 Salicylates 10.2 Gout Therapy 10.3 Other Rheumatologicals 10.3.1 Corticosteroids 10.3.2 Miscellaneous Rheumatological Agents 10.3.3 Muscle Relaxants & Antispasmodic Therapy 10.4 Osteoporosis Therapy 11. Obstetric & Gynecology 11.1 Oral Contraceptives & Related Agents 11.1.2 Progestin Only 11.2 Oxytocics 11.3 Estrogens & Progestins 11.3.1 Progestins 11.3.2 Estrogens 11.3.3 Estrogen Combinations 11.4 Miscellaneous OB/GYN 11.4.1 Drugs to Treat Infertility/IVF Agents 11.4.2 Vaginal Cleanser/Anti-Infectives 11.4.3 Vaginal Antifungals 11.4.4 Specialized OB/GYN Drugs
12. Ophthalmology 12.1 Beta-Blockers 12.2 Cholinesterase Inhibitor Miotics 12.3 Direct Acting Miotics 12.4 Other Glaucoma Drugs 12.5 Oral Drugs for Glaucoma 12.6 Cycloplegic Mydriatics 12.7 Non-Steroidal Anti-Inflammatory Agents 12.8 Vasoconstrictor Decongestants 12.9 Antibiotics 12.10 Sulfonamides 12.11 Steroids 12.12 Steroid-Antibiotic Combinations 12.13 Steroid-Sulfonamide Combinations 12.14 Sympathomimetics 12.15 Miscellaneous Ophthalmologics 12.16 Antivirals 13. Respiratory, Allergy, Cough & Cold 13.1 Antihistamine & Antiallergenic Agents 13.1.1 Antihistamines 13.1.2 Adrenergics 13.1.3 Corticosteroids 13.2 Cough & Cold Therapy 13.2.1 Antitussive Combinations 13.2.2 Expectorant Combinations 13.2.3 Decongestant/Antihistamines 13.3 Pulmonary Agents 13.3.1 Xanthines 13.3.2 Beta Agonists Oral 13.3.3 Beta Agonists Inhalers 13.3.4 Inhaled Corticosteroids 13.3.5 Intranasal Steroids 13.3.6 Miscellaneous Pulmonary Agents 14. Urologicals 14.1 Cholinergic Stimulants 14.2 Anticholinergics & Antispasmodics 14.3 Urinary Anesthetics 14.4 Miscellaneous Urologicals 15. Vitamins, Hematinics & Electrolytes 15.1 Vitamins & Hematinics 15.2 Coagulation Therapy 15.2.1 Anticoagulants 15.2.2 Antiplatelet Drugs 15.2.3 Heparin 15.2.4 Vitamin K 15.2.5 Hemostatics 15.2.6 Miscellaneous Coagulation Agents 15.3 Electrolytes 15.4 Miscellaneous Vitamins, Hematinics & Electrolytes 16. Diagnostics & Miscellaneous 16.1 Miscellaneous Agents 16.2 Smoking Deterrents 16.4 Miscellaneous Agents 16.6 Irrigation Solutions 16.7 Enzymes 16.9 Local Anesthetics
Decision and Order 127 F.T.C.
APPENDIX A
INTRODUCTION
The Universal Formulary is a list of FDA approved, prescription drug medications which was developed by an independent Pharmacy and Therapeutics (P&T) Committee comprised of distinguished health care professionals. Use of the formulary will assist in maintaining the quality of patient care and cost containment for the patient's drug benefit plan. Providers, participating physicians and pharmacists, are requested to refer to the Universal Formulary when selecting prescription drug therapy for eligible plan members.
Physicians are requested to prescribe medications included in the formulary whenever possible. Information on geriatric prescribing provides suggested alternatives for prescriptions that may pose particular risk to elderly persons.
The Universal Formulary is divided into major therapeutic categories (chapters) for easy use. Products that are approved for more than one therapeutic indication may be included in more than one chapter. Formulary drugs are identified by generic names. Brand names are included only for reference. Dependent upon the number of branded products, not all branded names are identified, but are deemed on the formulary. Due to the numerous generic and branded drugs in category 13.2, Cough & Cold Therapy, the formulary only lists examples of medications in this group.
FORMULARY MEDICATION COVERAGE
All drugs included in the formulary are not necessarily covered by each patient's prescription drug benefit plan design. Patients should consult their policies or customer service representatives to determine specific coverage.
• Approved Medications
Only FDA-approved medications are eligible for coverage under the participant's or employer's policy.
• Experimental Indications
Medications used for experimental indications are not eligible for coverage.
• Over-the-counter (OTC) Medications
Most benefit plans do not cover over-the-counter (non-prescription) medications. When a drug is available in the identical strength and dosage form as both a prescription and non-prescription drug, the prescription drug is usually not covered by the plan. In these cases, providers should refer the patient to the equivalent OTC product. In some instances, OTC medications are listed in the Universal Formulary for reference purposes only.
• Prior Authorization
Prior Authorization is necessary for certain medications. Based on current medical information, the P&T Committee has established clinical criteria for specific drug therapies that require the physician to provide patient-specific information before the drug would be permitted to be covered. Prior Authorized drugs often include those with potential for significant toxicity, inappropriate use and exceptionally high cost.
MERCK & CO., INC., ET AL.
Decision and Order
APPENDIX A
GENERIC DRUG SUBSTITUTION
Generic drugs are increasingly available as less costly equivalents to brand name drugs. Drugs which are available generically are designated in the formulary by a plus (+) sign. Brand name drugs are listed for reference purposes only. Unless medically necessary, physicians are encouraged to allow generic substitution when possible. When generic equivalents are available, pharmacists are encouraged to dispense generic products unless otherwise prohibited.
Most plan participants will have a lower copayment for generic alternatives. Some participants' plan designs may require generic substitution when an equivalent generic drug is available. In these plans, drugs which are available generically are subject to specific reimbursement levels, such as Maximum Allowable Cost (MAC) or Federal Upper Limit (FUL) price reimbursements. Depending on the participant's plan design, if the patient or physician requests the brand name drug, the participant may be required to pay the cost difference between the brand name drug price and the MAC or FUL reimbursement price, in addition to the plan's copayment requisites. In all instances, the pharmacist is reminded to follow state regulations regarding generic substitution.
COPAYMENTS
The participant's prescription drug benefit policy determines the applicable copayment for the covered prescriptions.
KEY TO SYMBOLS
Symbols used throughout the document have these definitions:
+ Use generic, brand listed for reference only: MAC reimbursement applies to some or all dosage forms and strengths. ▲ Use in the elderly is associated with increased risk; safer alternatives may be available. If used, dosage should generally be lowered. ↓ Dosage reduction may be required in elderly patients.
RELATIVE COST INDICATORS
Within each category, drug names are followed by a series of one or more dollar signs ($$) and/or one or more exclamation points (!!) that represent the approximate cost (including, where applicable, discounts or other cost containment factors) of that prescription to the health plan. Such cost indicators are generally based upon the estimated cost for a one-day supply of comparable dosage for each drug in the category, although other bases for comparison may be used when appropriate. Example:
$ Less than $1.00/day $$ Less than $2.00/day $$$ Less than $3.00/day $$$$ Less than $4.00/day $$$$$ Less than $5.00/day $$$$$! Less than $10.00/day $$$$$!! Less than $15.00/day $$$$$!!! Less than $20.00/day $$$$$!!!! Less than $25.00/day $$$$$!!!!! More than $25.00/day
Decision and Order 127 F.T.C.
APPENDIX A
1. ANTI-INFECTIVES
1.1 PENICILLINS GENERIC BRAND REL. COST NAME NAME VALUE +amoxicillin +Amoxil, Trimox, $ Polymox +ampicillin +Polycillin, Omnipen, $ Totacillin +penicillin VK +Pen-Vee K, $ Beepen-VK +dicloxacillin +Dynapen $$ penicillin G Wycillin $$$$ procaine (inj) amoxicillin/clavulanate Augmentin $$$$$! carbenicillin Geocillin $$$$$!
1.2 TETRACYCLINES GENERIC BRAND REL. COST NAME NAME VALUE +doxycycline +Vibramycin, Bio-Tab, $ Monodox +tetracycline +Sumycin, Achromycin $ +minocycline +Minocin, Dynacin $$ demeclocycline Declomycin $$$$$!!!
1.3 CEPHALOSPORINS GENERIC BRAND REL. COST NAME NAME VALUE 1.3.1 FIRST GENERATION CEPHALOSPORINS +cephalexin +Keflex, Keftab $$ +cephradine +Anspor, Velosef $$ +cefadroxil +Duricef, Ultracef $$$$$!
1.3.2 SECOND GENERATION CEPHALOSPORINS +cefaclor +Ceclor $$$$ cefpodoxime Vantin $$$$$! cefprozil Cefzil $$$$$! cefuroxime axetil Ceftin $$$$$!
1.3.3 THIRD GENERATION CEPHALOSPORINS cefixime Suprax $$$$$!
1.3.4 CARBACEPHEMS loracarbef Lorabid $$$$$!
1.4 ERYTHROMYCINS & OTHER MACROLIDES GENERIC BRAND REL. COST NAME NAME VALUE +erythromycin base, +E-Mycin, Ery-Tab $ film & enteric coated tabs +erythromycin +EES, EryPED $ ethylsuccinate +erythromycin stearate +Erythrocin $ +erythromycin estolate +Ilosone $$ +EES w/sulf +Pediazole $$$ +erythromycin base, +ERYC $$$ delayed release erythromycin polymer PCE $$$$ coated azithromycin Zithromax* $$$$$ dirithromycin Dynabac $$$$$ clarithromycin Biaxin $$$$$! *adjusted for therapy length.
1.5 QUINOLONES GENERIC BRAND REL. COST NAME NAME VALUE norfloxacin Noroxin $$$$$ ciprofloxacin Cipro $$$$$! enoxacin Penetrex $$$$$! lomefloxacin Maxaquin $$$$$! levofloxacin Levaquin $$$$$! ofloxacin Floxin $$$$$!
1.6 SULFAS & RELATED AGENTS GENERIC BRAND REL. COST NAME NAME VALUE +sulfamethoxazole/ +Bactrim, Bactrim DS, $ trimethoprim Septra, Septra DS +sulfasalazine +Azulfidine $ +sulfisoxazole +Gantrisin $ trisulfapyrimidine Triple Sulfa No. 2 $ sulfacycline Renoquid $$ sulfanilamide Sulfanilamide $$ sulfamethoxazole Gantanol $$$ +sulfadiazine +Sulfadiazine $$$$ +sulfisoxazole/ +Pediazole $$$$$! erythromycin
+Use generic; brand name listed for reference only. ^Use in the elderly is associated with increased risk. !Dosage reduction may be required in the elderly.
+Use generic; brand name listed for reference only. ^Use in the elderly is associated with increased risk. !Dosage reduction may be required in the elderly.
MERCK & CO., INC., ET AL. 175
156 Decision and Order
APPENDIX A
1.7 URINARY TRACT AGENTS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +methenamine mandelate | +Mandelamine | $ | | +nitrofurantoin macrocrystals | +Macrodantin | $ | | +phenazopyridine | +Pyridium | $ | | potassium citrate | Urocit-K | $ | | +trimethoprim | +Proloprim | $ | | methenamine hippurate | Hiprex, Urex | $$ | | nitrofurantoin monohydrate macrocrystals | Macrobid | $$$ | | acetohydroxamic acid | Lithostat | $$$$$ | | nalidixic acid | NegGram | $$$$$! | | nitrofurantoin | Furadantin | $$$$$!! |
1.9 ANTIFUNGAL AGENTS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | griseofulvin, microcrystalline | Grifulvin V, Grisactin, Fulvicin U/F | $ | | griseofulvin, ultramicrocrystalline | Grisactin Ultra, Gris-PEG, Fulvicin P/G | $ | | +nystatin | +Mycostatin, Nilstat | $ | | clotrimazole | Mycelex troche | $$$$ | | ketoconazole | Nizoral | $$$$ | | ampho B oral susp | Fungizone | $$$$$! | | fluconazole | Diflucan | $$$$$! | | terbinafine oral | Lamisil | $$$$$! | | itraconazole | Sporanox | $$$$$!! | | itraconazole soln | Sporanox | $$$$$!! | | flucytosine | Ancobon | $$$$$!!!! |
1.8 ANTIVIRALS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | 1.8.1. MISCELLANEOUS ANTIVIRALS | | | | +amantadine | +Symmetrel, Symadine | $ | | rimantadine | Flumadine | $$$ | | +acyclovir | +Zovirax | $$$$$ | | valacyclovir | Valtrex | $$$$$! | | famciclovir | Famvir | $$$$$!! | | ganciclovir | Cytovene | $$$$$!!!!! | | 1.8.2. HIV/AIDS THERAPY | | | | delavirdine | Rescriptor | $$$$$! | | didanosine (ddI) | Videx | $$$$$! | | lamivudine | Epivir | $$$$$! | | nevirapine | Viramune | $$$$$! | | stavudine | Zerit | $$$$$! | | zalcitabine (ddC) | HIVID | $$$$$! | | zidovudine (AZT) | Retrovir | $$$$$! | | indinavir | Crixivan | $$$$$!! | | nelfinavir | Viracept | $$$$$!!! | | ritonavir | Norvir | $$$$$!!! | | saquinavir | Invirase | $$$$$!!! |
1.10 VANCOMYCIN | GENERIC NAME | BRAND NAME | REL. COST VALUE | | vancomycin | Vancocin | $$$$$!!!!! |
1.11 MISCELLANEOUS ANTI-INFECTIVES | GENERIC NAME | BRAND NAME | REL. COST VALUE | | 1.11.1 MISCELLANEOUS ANTI-INFECTIVES | | | | dapsone | Dapsone | $ | | +neomycin | +Neomycin | $ | | chloramphenicol | Chloromycetin | $$$ | | +clindamycin | +Cleocin HCl | $$$ | | 1.11.2 ANTIPARASITICS | | | | +metronidazole | +Flagyl, Protostat | $ | | piperazine | Piperazine | $ | | +pyrantel | +Antiminth | $ | | iodoquinol | Yodoxin | $$ | | +mebendazole | +Vermox | $$$ | | thiabendazole | Mintezol | $$$ | | furazolidone | Furoxone | $$$$$! | | paromomycin sulfate | Humatin | $$$$$!! | | ivermectin | Stromectol | $$$$$!!! | | oxamniquine | Vansil | $$$$$!!!! | | praziquantel | Biltricide | $$$$$!!! | | pentamidine isethionate (inh) | Nebupent, Pentam | $$$$$!!!! | | atovaquone | Mepron | $$$$$!!!!! | | diethylcarbamazine | Hetrazan | $$$$$!!!!! |
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
Decision and Order 127 F.T.C.
APPENDIX A
1.1.13 ANTIMALARIALS primaquine Primaquine S pyrimethamine Daraprim S +quinine sulfate +Quinnam S chloroquine Aralen SS +hydroxychloroquine +Plaquenil SS sulfadoxine/ pyrimethamine Fansidar SS mefloquine Lariam SS chloroquine/primaquine Aralen/Primaquine SSS quinacrine Atabrine SSSSS!!!!!
1.1.14 ANTIMYCOBACTERIALS clofazimine Lamprene S INH/B6 Niazid B6 S +isoniazid +INH S pyrazinamide Pyrazinamide SSSS +rifampin +Rifadin SSSS ethambutol Myambutol SSSSS INH/rifampin Rifamate SSSSS aminosalicylic acid Paser SSSSS! cycloserine Seromycin SSSSS! ethionamide Trecator-SC SSSSS! INH/rifampin/PZA Rifater SSSSS! rifabutin Mycobutin SSSSS!
1.1.15 AMINOGLYCOSIDES +neomycin +Mycifradin tabs S
2. ANTINEOPLASTICS & IMMUNOSUPPRESSANT DRUGS
2.1 ANTINEOPLASTICS & IMMUNOSUPPRESSANT DRUGS GENERIC BRAND REL. COST NAME NAME VALUE All oral medications in this category are included in the formulary. The following are examples:
2.1.1 ALKYLATING AGENTS busulfan Myleran SSS chlorambucil Leukeran SSSS cyclophosphamide Cytoxan, Neosar SSSSS! melphalan Alkeran SSSSS! uracil mustard Uracil Mustard SSSSS!! lomustine CeeNU SSSSS!!!!!!
2.1.2 ANTIMETABOLITES +methotrexate +Rheumatrex, SS Methotrexate +fluorouracil +Adrucil SSS mercaptopurine Purinethol SSSSS +cytarabine +Cytarabine, Cytosar-U SSSSS! floxuridine FUDR SSSSS! thioguanine Thioguanine, 6-TG SSSSS! fludarabine Fludara SSSSS!!!!!
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ♦Dosage reduction may be required in the elderly.
2.1.3 ANDROGENS, ESTROGENS, HORMONES & RELATED DRUGS
2.1.3.1 ANDROGENS +fluoxymesterone +Halotestin SS testolactone Teslac SSSSS!!
2.1.3.2 ESTROGENS chlorotrianisene Tace SS
2.1.3.3 HORMONES +megestrol +Megace SS
2.1.3.4 ANTIESTROGENS tamoxifen Nolvadex SSSS anastrozole Arimidex SSSSS! letrozole Femara SSSSS!
2.1.3.5 ANTIANDROGENS flutamide Eulexin SSSSS! nilutamide Nilandron SSSSS! bicalutamide Casodex SSSSS!!
2.1.5 IMMUNOSUPPRESSANT DRUGS +azathioprine +Imuran SSS cyclosporine Sandimmune SSSSS!! cyclosporine Neoral SSSSS!! microemulsion mycophenolate mofetil CellCept SSSSS!! tacrolimus Prograf SSSSS!!!
2.1.6 MISCELLANEOUS ANTINEOPLASTIC DRUGS +hydroxyurea +Hydrea SSS procarbazine Matulane SSS mitotane Lysodren SSSSS!! estramustine Emcyt SSSSS!!! all-trans retinoic acid, Vesanoid SSSSS!!!!! tretinoin altretamine Hexalen SSSSS!!!!! etoposide VePesid, Toposide SSSSS!!!!!
2.2 ADJUNCTIVE AGENTS GENERIC BRAND REL. COST NAME NAME VALUE
2.2.1 ADJUNCTIVE AGENTS medroxyprogesterone Depo-Provera SS (inj) +folinic acid +Leucovorin Cal SSS levamisole Ergamisol SSSSS! leuprolide (inj) Lupron SSSSS!!!! erythropoietin (inj) Epogen, Procrit SSSSS!!!!! filgrastim (G-CSF) (inj) Neupogen SSSSS!!!!! octreotide (inj) Sandostatin SSSSS!!!!! sargramostim Leukine SSSSS!!!!! (GM-CSF) (inj)
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ♦Dosage reduction may be required in the elderly.
MERCK & CO., INC., ET AL.
Decision and Order APPENDIX A
3. AUTONOMIC & CNS DRUGS, NEUROLOGY & PSYCH
3.1 NARCOTIC ANALGESICS GENERIC BRAND REL. COST NAME NAME VALUE 3.1.1 NARCOTICS +methadone +Dolophine $ MS oral concentrate OMS $ +hydromorphone +Dilaudid $$ levorphanol Levo Dromoran $$ +codeine +Codeine $$$ +meperidine +Demerol $$$ morphine sulfate, Morphine Sulfate $$$ soluble tabs opium B&O Supprettes $$$$$ fentanyl transdermal Duragesic $$$$$! hydrocodone Banacap HC $$$$$! levomethadyl ORLAAM $$$$$! morphine sulfate, MS Contin $$$$$! controlled release morphine sulfate supp RMS Supp $$$$$! oxycodone OxyContin, Roxicodone $$$$$! fentanyl lozenges Fentanyl Oralet $$$$$!!!!!
3.1.2 COMBINATION NARCOTIC/ANALGESICS +apap/butalbital/ +Fioricet, Esgic, Triad $ caffeine +apap/codeine +Tylenol/codeine, $ Margesic, Phenaphen +asa/codeine +Empirin/codeine $ +asa w oxycodone +Percodan $ +asa/butalbital/caffeine +Fiorinal, Fiorigen PF $ +hydrocodone/apap +Vicodin, Lortab $ +apap/butalbital +Phenilin Forte, $$ Axotal, Phenilin +apap/oxycodone +Tylox $$ capsule +apap/oxycodone tablet +Percocet, Roxicet $$$ asa/butalbital/caffeine/ Fiorinal w/Codeine $$$$$! codeine asa/dihydrocodeine Synalgos-DC, $$$$$!! DHC Plus
1 apap = acetaminophen 2 asa = aspirin
3.2 PROPOXYPHENE ▲ GENERIC BRAND REL. COST NAME NAME VALUE ▲+propoxyphene +Darvon $ ▲+propoxyphene +Wygesic $ HCl/apap¹ ▲+propoxyphene +Darvocet N-100 $ napsylate/apap ▲+propoxyphene/ +Propoxyphene $$ asa/caffeine Compound, Darvon Cpd-65
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
3.3 NON-NARCOTIC ANALGESICS GENERIC BRAND REL. COST NAME NAME VALUE 3.3.1 NSAIDs +fenoprofen +Nalfon $ +ibuprofen +Motrin, Rufen $ +*indomethacin +Indocin $ +meclofenamate +Meclomen $ +naproxen +Naprosyn $ +naproxen sod +Anaprox, $ Anaprox DS, Naprelan +piroxicam +Feldene $ +sulindac +Clinoril $ +diclofenac +Voltaren $$ +flurbiprofen +Ansaid $$ +ibuprofen suspension +Children's Advil, $$ Children's Motrin ▲+indomethacin SR +Indocin SR $$ +tolmetin +Tolectin $$ +etodolac +Lodine $$$ +ketoprofen +Orudis $$$ +ketoprofen SR +Oruvail $$$ nabumetone Relafen $$$ oxaprozin Daypro $$$ diclofenac potassium Cataflam $$$$$ +ketorolac +Toradol $$$$$ ketorolac (inj) Toradol $$$$$!!!!!
3.3.2 SALICYLATES salicylamide Saleto-D $ +salsalate +Salsflex $ +sodium salicylate +Sodium Salicylate $ asa sustained release Zorprin $$ +choline magnesium +Trilisate $$ salicylate magnesium salicylate Mobidin $$ +diflunisal +Dolobid $$$ salicylate salts Arthtopan $$$
3.3.3 MISCELLANEOUS ANALGESICS tramadol Ultram $$$ pentazocine/apap Talacen $$$$ +pentazocine/naloxone +Talwin Nx $$$$ pentazocine Talwin $$$$$ buprenorphine (inj) Buprenex $$$$$!! butorphanol (inj) Stadol $$$$$!! butorphanol NS Stadol NS $$$$$!!!!!
3.3.4 NARCOTIC ANTAGONISTS naltrexone Trexan, ReVia $$$$$ +naloxone (inj) +Narcan $$$$$!
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
Decision and Order 127 F.T.C.
APPENDIX A
3.4 MIGRAINE & CLUSTER HEADACHE THERAPY | GENERIC NAME | BRAND NAME | REL. COST VALUE | |---|---|---| | 3.4.1 HEADACHE THERAPY | | | | +apap/butalbital/ caffeine | +Fioricet, Esgic, Triad | $ | | +butalbital/apap | +Phrenilin Forte, Phrenilin | $ | | ergoloid mesylates | Hydergine LC | $ | | +asa/butalbital/caffeine | +Fiorinal, Fiorigen PF | $$ | | ergotamine | Ergotat, Ergomar | $$ | | +isometheptene/ dichloralphenazone/ apap | +Midrin | $$ | | +ergotamine/caffeine | +Cafergot | $$$$ | | methysergide | Sansert | $$$$! | | sumatriptan (nasal) | Imitrex | $$$$! | | dihydroergotamine (inj) | D.H.E.45 | $$$$!! | | sumatriptan (tabs) | Imitrex | $$$$! | | sumatriptan (inj) | Imitrex | $$$$!!!!! | | 3.4.2 ANTIVERTIGO & ANTIEMETIC DRUGS | | | | +meclizine | +Antivert, Medivert, Vertin | $ | | ▲+promethazine | ▲+Phenergan | $ | | buclizine | Bucladin-S | $$ | | scopolamine | Transderm-Scop | $$ | | thiethylperazine | Torecan | $$ | | +trimethobenzamide | +Tigan | $$ | | +prochlorperazine | +Compazine | $$$$ | | promazine | Sparine | $$$$ | | +trimethobenzamide (supp) | +Tigan | $$$$ | | +trimethobenzamide (inj) | +Tigan | $$$$! | | +prochlorperazine (supp) | +Compazine | $$$$!! | | ▲+promethazine (supp) | ▲+Phenergan | $$$$!! | | dronabinol | Marinol | $$$$!!! | | granisetron | Kytril | $$$$!!!!! | | ondansetron | Zofran | $$$$!!!!! |
3.5 ANTIPARKINSONISM AGENTS | GENERIC NAME | BRAND NAME | REL. COST VALUE | |---|---|---| | +amantadine | +Symmetrel | $ | | +benztropine | +Cogentin | $ | | biperiden | Akineton | $ | | +diphenhydramine | +Benadryl | $ | | procyclidine | Kemadrin | $ | | +trihexyphenidyl | +Artane | $ | | +carbidopa-levodopa | +Sinemet | $$ | | +bromocriptine mesylate | +Parlodel | $$$$ | | carbidopa-levodopa CR | Sinemet CR | $$$$ | | +selegiline | +Eldepryl | $$$$ | | pramipexole | Mirapex | $$$$ | | levodopa | Dopar, Larodopa | $$$$! | | pergolide mesylate | Permax | $$$$! |
+ Use generic; brand name listed for reference only. ▲ Use in the elderly is associated with increased risk. ↓ Dosage reduction may be required in the elderly.
3.6 ANTICONVULSANTS | GENERIC NAME | BRAND NAME | REL. COST VALUE | |---|---|---| | +carbamazepine | +Tegretol | $ | | mephenytoin | Mesantoin | $ | | mephobarbital | Mebaral | $ | | +phenobarbital | +Phenobarbital, Solfoton | $ | | phenytoin | Dilantin | $ | | +primidone | +Mysoline | $ | | +valproic acid | +Depakene | $ | | +clonazepam | +Klonopin | $$ | | magnesium sulfate (inj) | Magnesium Sulfate | $$ | | phenacemide | Phenurone | $$ | | trimethadione | Tridione | $$ | | divalproex sodium | Depakote | $$$ | | +ethosuximide | +Zarontin | $$$ | | methsuximide | Celontin | $$$ | | paramethadione | Paradione | $$$ | | phensuximide | Milontin | $$$ | | ethotoin | Peganone | $$$$ | | gabapentin | Neurontin | $$$$ | | felbamate | Felbatol | $$$$! | | lamotrigine | Lamictal | $$$$! | | topiramate | Topamax | $$$$! | | diazepam gel | Diastat | $$$$!!!!! |
3.7 MISCELLANEOUS NEUROLOGICAL THERAPY | GENERIC NAME | BRAND NAME | REL. COST VALUE | |---|---|---| | donepezil | Aricept | $$$$ | | tacrine | Cognex | $$$$ | | midodrine | ProAmatine | $$$$! | | glatiramer (inj) | Copaxone | $$$$!!!!! | | riluzole | Rilutek | $$$$!!!!! |
+ Use generic; brand name listed for reference only. ▲ Use in the elderly is associated with increased risk. ↓ Dosage reduction may be required in the elderly.
MERCK & CO., INC., ET AL.
Decision and Order APPENDIX A
3.8 MUSCLE RELAXANTS & ANTISPASMODIC THERAPY GENERIC BRAND REL. COST NAME NAME VALUE 3.8.1 MUSCLE RELAXANTS & ANTISPASMODIC THERAPY +*carisoprodol +Soma $ +*chlorzoxazone +Paraflex, Parafon $ Forte DSC +*cyclobenzaprine +Flexeril $ +*diazepam +Valium $ +*meprobamate +Miltown, Equanil $ +*methocarbamol +Robaxin $ +*oxybutynin +Ditropan $ +*baclofen +Lioresal $$ Δmetaxalone Skelaxin $$$ +asa/orphenadrine +Norgesic $$$$ dantrolene Dantrium $$$$ +orphenadrine +Norflex $$$$ asa/carisoprodol/ Soma Comp/Codeine $$$$$! codeine
1 Refer also to Anxiolytics (3.9.5)
3.8.2 MYASTHENIA GRAVIS neostigmine (inj) Prostigmin $$ pyridostigmine (inj) Mestinon $$ ambenonium Mytelase $$$$$
3.9 PSYCHOTHERAPEUTIC DRUGS GENERIC BRAND REL. COST NAME NAME VALUE 3.9.1 HYPNOTIC AGENTS +chloral hydrate +Aquachloral $ +*estazolam +ProSom $ +*flurazepam +Dalmane $ +*temazepam +Restoril $ +*triazolam +Halcion $ ↓zolpidem Ambien $$ quazepam Doral $$$
3.9.2 ANTIDEPRESSANT AGENTS 3.9.2.1 TRICYCLICS +*amitriptyline +Elavil, Endep $ +*desipramine +Norpramin, Pertofrane $ +*doxepin +Sinequan, Adapin $ +*imipramine +Tofranil $ +*nortriptyline +Pamelor, Aventyl $ +*amoxapine +Asendin $$ +*protriptyline +Vivactil $$ ↓*clomipramine +Anafranil $$$
3.9.2.2 MISCELLANEOUS ANTIDEPRESSANTS ↓*maprotiline +Ludiomil $ ↓*trazodone +Desyrel $ ↓bupropion Wellbutrin $$$ mirtazapine Remeron $$$ ↓nefazodone Serzone $$$ ↓venlafaxine Effexor $$$
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
3.9.2.3 MAO INHIBITORS phenelzine Nardil $$ tranylcypromine Parnate $$$
3.9.2.4 SELECTIVE SEROTONIN REUPTAKE INHIBITORS ↓paroxetine Paxil $$$ ↓sertraline Zoloft $$$ ↓fluoxetine Prozac $$$$ ↓fluvoxamine Luvox $$$$
3.9.3 ANTIPSYCHOTICS GENERIC BRAND REL. COST NAME NAME VALUE 3.9.3.1 PHENOTHIAZINES +chlorpromazine +Thorazine $ +fluphenazine +Prolixin, Permitil $ +perphenazine +Trilafon $ +thioridazine +Mellaril, Mellaril S $ acetophenazine Tindal $$ mesoridazine Serentil $$ +trifluoperazine +Stelazine $$
3.9.3.2 BUTYROPHENONES +haloperidol +Haldol $
3.9.3.3 MISCELLANEOUS ANTIPSYCHOTICS +thiothixene +Navane $ pimozide Orap $$ +loxapine +Loxitane, Loxitane C $$$ molindone Moban $$$ risperidone Risperdal $$$$$ clozapine Clozaril $$$$$! olanzapine Zyprexa $$$$$!
3.9.4 MISCELLANEOUS PSYCHOTHERAPEUTIC AGENTS +diethylpropion +Tenuate $ +lithium carb (capsule) +Eskalith, Lithonate $ +lithium carb (tablet) +Eskalith, Lithotabs $ +lithium citrate +Lithium Citrate $ +phentermine +Ionamin, Fastin $ benzphetamine Didrex $$ +methylphenidate +Ritalin $$ +perphenazine/ +Triavil $$ amitriptyline amphetamines¹ Dexedrine, Desoxyn $$$ +chlordiazepoxide/ +Limbitrol $$$ amitriptyline methamphetamine Desoxyn $$$ pemoline Cylert $$$ +phendimetrazine +Phenazine, Adipost $$$ mazindol Mazanol $$$$ meprobamate/ Deptrol $$$$ benctyzine
1 For narcolepsy and attention deficit disorder only.
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
Decision and Order 127 F.T.C.
APPENDIX A
3.9.5 ANXIOLYTICS ↓+alprazolam +Xanax $ +chlordiazepoxide +Librium $ ↓+clorazepate +Tranxene, Gen-Xene $ ↓++diazepam +Valium $ ↓+lorazepam +Ativan $ +meprobamate +Meprospan $ ++oxazepam +Serax $ buspirone BuSpar $$$$ paraldehyde Paral $$$$
3.9.6 BARBITURATES amobarbital/ secobarbital Tuinal $ mephobarbital Mebaral $
4. CARDIOVASCULAR, HYPERTENSION & LIPIDS
4.1 ANTIARRHYTHMIC AGENTS GENERIC BRAND REL. COST NAME NAME VALUE ▲+disopyramide +Norpace $ +procainamide +Pronestyl $ +quinidine 200 sulfate +Quinidine Sulfate $ +quinidine gluconate +Quinaglute $ +procainamide SR +Procan SR, $ Procanbid Pronestyl SR ▲+disopyramide CR +Norpace CR $$ +quinidine 300 sulfate +Quinora $$ +quinidine ER +Quinidex $$ flecainide Tambocor $$$ +mexiletine +Mexitil $$$ moricizine Ethmozine $$$ tocainide Tonocard $$$ propafenone Rythmol $$$$ quinidine Cardioquin $$$$ polygalacturonate amiodarone Cordarone $$$$$ sotalol Betapace $$$$$
4.2 CARDIAC GLYCOSIDES GENERIC BRAND REL. COST NAME NAME VALUE +digoxin Lanoxicaps, +Lanoxin $
4.3 NITRATES GENERIC BRAND REL. COST NAME NAME VALUE 4.3.1 RAPID ACTING NITRATES nitroglycerin SL Nitrostat $ nitroglycerin spray Nitrolingual Spray $$
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
4.3.2 LONG ACTING NITRATES +isosorbide dinitrate +Isordil $ nitroglycerin Nitrogard $ nitroglycerin ointment Nitrol, Nitro-Bid $ nitroglycerin (oral) Nitrobid $ +isosorbide dinitrate SR +Dilatrate-SR, $$ Isordil Tembids isosorbide mononitrate Imdur $$ isosorbide mononitrate Ismo $$ isosorbide mononitrate Monoket $$ +transdermal Nitro-Dur, $$ nitroglycerin patch Transderm-Nitro, Deponit, Minitran, Nitrodisc
4.4 COAGULATION THERAPY GENERIC BRAND REL. COST NAME NAME VALUE 4.4.1 ANTICOAGULANTS anisiodione Miradon $ dicumarol Dicumarol $ +warfarin +Coumadin $
4.4.2 ANTIPLATELET DRUGS ▲+dipyridamole +Persantine $ ticlopidine Ticlid $$$$
4.4.3 HEPARIN +heparin (inj) +Heparin $$$ enoxaparin (inj) Lovenox $$$$$!!!!!
4.4.4 VITAMIN K phytonadione Mephyton $
4.4.5 HEMOSTATICS aminocaproic acid Amicar $$
4.4.6 MISCELLANEOUS COAGULATION AGENTS +pentoxifylline +Trental $$
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
MERCK & CO., INC., ET AL.
Decision and Order
APPENDIX A
4.5 ANTIHYPERTENSIVE THERAPY GENERIC BRAND REL. COST NAME NAME VALUE 4.5.1 THIAZIDE & RELATED DIURETICS amiloride Midamor $ ↓+amiloride/HCTZ +Moduretic $ bendroflumethiazide Naturetin-5 $ benzthiazide Exna $ +bumetanide +Bumex $ ↓+chlorthalidone +Hygroton $ deserpidine/HCTZ Oreticyl $ deserpidine/ Enduronyl $ methyclothiazide ethacrynic acid Edecrin $ +furosemide +Lasix $ ↓+hydrochlorothiazide +HydroDIURIL, Oretic, $ Esidrix +indapamide +Lozol $ ▲+methyclothiazide +Enduron, Aquatensen $ metolazone Zaroxolyn, Mykrox $ +spironolactone +Aldactone $ ↓+spironolactone/ +Aldactazide $ HCTZ torsemide Demadex $ triamterene Dyrenium $ ↓+triamterene/HCTZ +Maxzide, Dyazide $ polythiazide Renese $$
4.5.2 BETA BLOCKERS +atenolol +Tenormin $ betaxolol Kerlone $ bisoprolol Zebeta $ +metoprolol +Lopressor $ metoprolol LA Toprol XL $ +nadolol +Corgard $ +pindolol +Visken $ +propranolol +Inderal $ +propranolol LA +Inderal LA $ +timolol +Blocadren $ +acebutolol +Sectral $$ carteolol Cartrol $$ labetalol Normodyne, Trandate $$ carvedilol Coreg $$$$
4.5.3 CALCIUM CHANNEL BLOCKERS +diltiazem +Cardizem, $ +Tiazac felodipine Plendil $ +nifedipine +Procardia, Adalat $ nisoldipine Sular $ +verapamil +Calan, Isoptin $ +verapamil SR +Calan SR, Isoptin SR $ amlodipine Norvasc $$ diltiazem CD Cardizem CD $$ +diltiazem SR +Cardizem SR, $$ +Dilacor XR isradipine DynaCirc $$ isradipine DynaCirc CR $$ controlled release mibefradil Posicor $$ nicardipine Cardene $$ nicardipine SR Cardene SR $$ nifedipine XL Adalat CC, $$ Procardia XL $$$ verapamil Covera-HS $$ verapamil, long acting Verelan $$ bepridil Vascor $$$$ nimodipine Nimotop $$$$$!!!!!
4.5.4 ACE INHIBITORS benazepril Lotensin $ fosinopril Monopril $ moexipril Univasc $ trandolapril Mavik $ +captopril +Capoten $$ enalapril Vasotec $$ lisinopril Prinivil, $$ Zestril quinapril Accupril $$ ramipril Altace $$
4.5.5 ADRENERGIC ANTAGONISTS & RELATED DRUGS +clonidine +Catapres $ +guanabenz +Wytensin $ ▲+methyldopa +Aldomet $ +prazosin +Minipress $ ▲+reserpine +Serpasil $ doxazosin Cardura $$ guanadrel Hylorel $$ guanethidine Ismelin $$ +guanfacine +Tenex $$ tamsulosin Flomax $$ terazosin Hytrin $$ clonidine transdermal Catapres-TTS $$$
4.5.6 AGENTS FOR PHEOCHROMOCYTOMA phenoxybenzamine Dibenzyline $$$$$ metyrosine Demser $$$$$! phentolamine Regitine $$$$$!!!!!
4.5.7 VASODILATORS +hydralazine +Apresoline $ +minoxidil +Loniten $ +papaverine +Pavabid $
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
Decision and Order 127 F.T.C.
APPENDIX A
4.5.8 OTHER ANTIHYPERTENSIVE COMBINATIONS +benazepril/HCTZ Lotensin HCT S +clonidine/ +Combipres S chlorthalidone +hydralazine/HCTZ +Apresazide S hydralazine/ SER-AP-ES, Unipres S reserpine/HCTZ +methyldopa/HCTZ +Aldoril S prazosin/polythiazide Minizide S +propranolol/HCTZ +Inderide S reserpine/chlorothiazide Diupres S +reserpine/HCTZ +Hydropres S +timolol/HCTZ Timolide S benazepril/amlodipine Lotrel SS +bisoprolol/HCTZ Ziac SS +captopril/HCTZ +Capozide SS enalapril/diltiazem Teczem SS enalapril/felodipine Lexxel SS extended release +enalapril/HCTZ Vaseretic SS +lisinopril/HCTZ Prinzide, SS Zestoretic +metoprolol/HCTZ Lopressor HCT SS +nadolol/ Corzide SS bendroflumethiazide reserpine/ Salutensin SS hydroflumethiazide trandolapril/ Tarka SS verapamil extended release
4.5.9 ANGIOTENSIN II RECEPTOR BLOCKERS losartan Cozaar SS losartan/HCTZ Hyzaar SS valsartan Diovan SS
4.6 LIPID/CHOLESTEROL LOWERING AGENTS GENERIC BRAND REL. COST NAME NAME VALUE +gemfibrozil +Lopid S +nicotinic acid +Niacin S colestipol Colestid SS dextrothyroxine Choloxin SS fluvastatin Lescol SS atorvastatin Lipitor SSS cholestyramine Questran, SSS Questran Light pravastatin Pravachol SSS simvastatin Zocor SSS lovastatin Mevacor SSSS
5. DERMATOLOGICALS/ TOPICAL THERAPY
5.1 TOPICAL CORTICOSTEROIDS GENERIC BRAND REL. COST NAME NAME VALUE
5.1.1 TOPICAL CORTICOSTEROIDS -- GROUP I (Very High Potency) betamethasone Diprolene SSSS dipropionate .05% (augmented) gel, ointment, cream +clobetasol .05% +Temovate SSSS cream, lotion, ointment halobetasol .05% Ultravate SSSS cream, ointment diflorasone .05% Psorcon, Florone SSSSS cream diflorasone .05% Psorcon, Florone SSSSS ointment
5.1.2 TOPICAL CORTICOSTEROIDS -- GROUP II (High Potency) +betamethasone +Diprosone, Maxivate SS dipropionate .05% ointment +desoximetasone +Topicort SS 0.25% cream, ointment amcinonide .1% Cyclocort SSS cream, lotion, ointment +desoximetasone +Topicort SSS 0.05% gel +fluocinonide .05% +Lidex SSS gel, ointment soln mometasone furoate Elocon ointment SSS 0.1% ointment halcinonide .025% Halog SSSS cream halcinonide 0.1% Halog SSSS cream, soln betamethasone Diprolene AF SSSSS dipropionate 0.5% (augmented) cream
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
MERCK & CO., INC., ET AL.
Decision and Order APPENDIX A
5.1.3. TOPICAL CORTICOSTEROIDS — GROUP III +betamethasone +Diprosone Aerosol $ dipropionate .1% aerosol +betamethasone +Diprosone, Maxivate $ -dipropionate 0.05% cream, lotion +betamethasone +Valisone $ valerate 0.1% ointment +fluocinonide 0.05% +Lidex, Lidex E $ cream +triamcinolone +Aristocort $ acetonide 0.5% cream, ointment fluticasone propionate Cutivate $$$ 0.005% ointment betamethasone Diprolene $$$$ dipropionate 0.05% lotion halcinonide Halog $$$$$ 0.1% ointment
5.1.6. TOPICAL CORTICOSTEROIDS — GROUP VI (Low Potency) +betamethasone valerate +Valisone $ 0.1% lotion +fluocinolone acetonide +Synalar $ 0.01% cream, soln +triamcinolone +Aristocort $ acetonide 0.025% cream, ointment +triamcinolone +Kenalog $ acetonide 0.025% lotion +triamcinolone +Aristocort $ acetonide 0.1% cream alclometasone Aclovate $$ dipropionate 0.05% cream, ointment +desonide 0.05% +DesOwen, $$ cream, ointment, Desonide cream lotion
5.1.4. TOPICAL CORTICOSTEROIDS — GROUP IV (Medium Potency) +desoximetasone +Topicort LP $ 0.05% cream +fluocinolone acetonide +Synalar $ 0.025% ointment +triamcinol +Aristocort $ acetonide 0.1% ointment clocortolone pivalate Cloderm $$ 0.1% cream flurandrenolide .05% Cordran, Cordran SP $$$ lotion, ointment flurandrenolide tape Cordran Tape Patch $$$ hydrocortisone valerate Westcort $$$ 0.2% ointment mometasone furoate Elocon $$$ 0.1% cream, lotion
5.1.7. TOPICAL CORTICOSTEROIDS — GROUP VII +hydrocortisone 2.5% +Dermacort, Hytone $ cream, ointment +hydrocortisone +Anusol HC $ suppos, cream dexamethasone 0.04 % Decaspray $$ aerosol +hydrocortisone 2.5% +Hytone $$$ lotion
Also see 8.3.3. for other steroid containing topicals.
5.1.5. TOPICAL CORTICOSTEROIDS — GROUP V +betamethasone valerate +Valisone $ 0.1% cream +betamethasone valerate +Valisone $ 0.01% cream +fluocinolone acetonide +Synalar $ 0.025% cream hydrocortisone Pandel $ buteprate 0.1% prednicarbate Dermatop Emollient $ +triamcinolone +Kenalog $ acetonide 0.1% lotion triamcinolone spray Kenalog S flurandrenolide Cordran SP $$ 0.05% cream fluticasone propionate Cutivate $$$ 0.05% cream hydrocortisone butyrate Locoid $$$ 0.1% cream, ointment, soln hydrocortisone valerate Westcort $$$ 0.2% cream betamethasone Uticort $$$$$!!!
5.2 TOPICAL ANESTHETICS GENERIC BRAND REL. COST NAME NAME VALUE doxepin Zonalon $ +lidocaine +Xylocaine, Viscous $ Xylocaine spray prilocaine/lidocaine EMLA $$$$ dyclonine Dyclone $$$$$!
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
Decision and Order 127 F.T.C.
APPENDIX A
5.3 THERAPY FOR ACNE | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +benzoyl peroxide | +Benzoyl peroxide, Desquam-X, Benzac | $ | | benzoyl peroxide | Triaz | $ | | +benzoyl peroxide gel | +Persa-Gel, Persa-Gel W | $ | | benzoyl peroxide/sulfa | BPO/Sulfur, Sulfoxyl Strong | $ | | +erythromycin gel | +Emgel, Erygel | $ | | erythromycin pledgettes | Erycette, T-STAT | $ | | +erythromycin T soln | +A/T/S, EryDerm, T-STAT | $ | | +clindamycin topical | +Cleocin T | $$ | | sodium sulfacetamide lotion | Klaron | $$ | | tetracycline | Topicylene | $$ | | adapalene | Differin | $$$ | | azelaic acid | Azelex | $$$ | | benzoyl peroxide/ erythromycin | Benzamycin 23 | $$$ | | metronidazole | MetroGel | $$$ | | sulfacetamide/sulfur | Sulfacet R, Novacet | $$$ | | tretinoin | Retin A | $$$ | | tretinoin | Retin A micro | $$$ | | benzoyl peroxide/ erythromycin | Benzamycin 46 | $$$$ | | meclocycline | Meclan | $$$$$ | | isotretinoin | Accutane | $$$$$! |
5.4 TOPICAL ANTIBACTERIALS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | bacitracin | Baciguent | $ | | +gentamicin cream, oint | +Garamycin | $ | | chloramphenicol | Chloromycetin | $$ | | mupirocin | Bactroban | $$$ | | neomycin/fluocinolone | Neosynalar | $$$ |
5.5 TOPICAL ANTIFUNGALS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +nystatin topical | +Mycostatin | $ | | +nystatin/triamcinolone | +Mycolog II | $ | | sodium thiosulfate | Tinver | $ | | amphotericin B | Fungizone | $$ | | clioquinol | Iodochlorhydroxyquin | $$ | | clotrimazole | Mycelex | $$ | | ketoconazole shampoo | Nizoral | $$ | | ciclopirox | Loprox | $$$ | | econazole | Spectazole | $$$ | | ketoconazole cream | Nizoral | $$$ | | naftifine | Naftin | $$$ | | oxiconazole | Oxistat | $$$ | | clotrimazole/ betamethasone | Lotrisone | $$$$ | | terbinafine cream | Lamisil | $$$$$ |
5.6 TOPICAL ANTIVIRALS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | penciclovir | Denavir | $$$$ | | acyclovir ointment | Zovirax | $$$$$ |
5.7 BURN THERAPY | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +silver sulfadiazine | +Silvadene, SSD | $ |
5.8 TOPICAL ENZYMES | GENERIC NAME | BRAND NAME | REL. COST VALUE | | trypsin | Granulex | $ |
5.9 KERATOLYTICS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | salicylic acid gel | Keralyt | $ |
+Use generic; brand name listed for reference only. ▲ Use in the elderly is associated with increased risk. ↓ Dosage reduction may be required in the elderly.
+Use generic; brand name listed for reference only. ▲ Use in the elderly is associated with increased risk. ↓ Dosage reduction may be required in the elderly.
MERCK & CO., INC., ET AL. 185
156 Decision and Order
APPENDIX A
5.10 ANTIPSORIATIC/ ANTISEBORRHEIC | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +selenium sulfide 2.5%, 1% | +Selsun Rx | S | | cloroxine | Capitrol | SS | | sulfacetamide lotion | Sebizon | SS | | anthralin | Dritho-scalp, Drithocreme | SSS | | calcipotriene | Dovonex | SSSSS! | | tazarotene gel | Tazorac | SSSSS! |
5.11 TOPICAL SCABICIDES/ PEDICULICIDES | GENERIC NAME | BRAND NAME | REL. COST VALUE | | benzyl benzoate lotion | Benzyl Benzoate | S | | +lindane | +Lindane, Kwell | S | | crotamiton | Eurax | SS | | permethrin | Elimite | SSSS |
5.12 MISCELLANEOUS DERMATOLOGICALS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | aluminum chloride | Drysol | S | | collagenase | Collagenase Santyl | S | | dihydroxyacetone | Vitadyne | S | | doxepin | Zonalon | S | | iodine | Iodine | S | | mafenide | Sulfamylon | S | | nitrofurazone | Furacin | S | | fibrinolysin | Elase | SS | | lactic acid | Lac-Hydrin | SS | | monobenzone | Benoquin | SS | | dextranomer | Debrisan | SSS | | hydroquinone | Eldopaque Forte, Eldoquin Forte | SSS | | hydroquinone/ sunscreen | Solaquin Forte | SSS | | sutilains | Travase | SSS | | fluorouracil | Efudex, Fluoroplex | SSSS | | hexachlorophene | Septisol Foam | SSSS | | imiquimod | Aldara | SSSSS | | podofilox | Condylox | SSSSS | | trioxsalen | Trisoralen | SSSSS | | masaprocol | Actinex | SSSSS! | | methoxsalen | Oxsoralen | SSSSS!! | | iodoquinal | Sebaquin | SSSSS!!!!! | | podophyllum | Podofin | SSSSS!!!!! | | sulfapyridine | Sulfapyridine | SSSSS!!!!! |
+ Use generic; brand name listed for reference only. ▲ Use in the elderly is associated with increased risk. ↓ Dosage reduction may be required in the elderly.
6. EAR, NOSE & THROAT MEDICATIONS
6.1 INTRANASAL STEROIDS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | beclomethasone pockethaler | Vancenase pockethaler | SS | | beclomethasone | Vancenase AQ, Vancenase DS, Beconase AQ | SS | | budesonide | Rhinocort | SS | | flunisolide | Nasalide | SS | | fluticasone | Flonase | SS | | dexamethasone | Dexacort Turbinaire | SSS | | triamcinolone | Nasacort | SSS | | triamcinolone acetonide | Nasacort AQ | SSS |
6.2 MISCELLANEOUS OTIC PREPARATIONS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +acetic acid | +VoSoL, Acetasol | S | | acetic acid/al acetate | Domeboro Otic | S | | +acetic acid w/HC | +VoSoL HC, Acetasol HC | S | | +antipyrine/benzocaine | +Auralgan | S | | chloramphenicol | Chloromycetin Otic | SSS | | triethanolamine oleate | Cerumenex | SSS |
6.3 OTIC STEROID/ANTIBIOTIC | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +neomycin/polymyxin/ HC | +Cortisporin | SS |
1 For patients allergic to neomycin, Tobrex ophthalmic or gentamicin are useful alternatives.
6.4 MISCELLANEOUS AGENTS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +chlorhexidine | +Peridex | S | | +hydrocortisone | +HCA in Orabase | S | | +triamcinolone in orabase | +Kenalog in Orabase | S | | cromolyn nasal | Nasalcrom | SS | | ipratropium | Atrovent Nasal Spray | SS | | +lidocaine viscous | +Viscous Xylocaine | SS |
+ Use generic; brand name listed for reference only. ▲ Use in the elderly is associated with increased risk. ↓ Dosage reduction may be required in the elderly.
Decision and Order 127 F.T.C.
APPENDIX A
7. ENDOCRINE/DIABETES
7.1 ANTITHYROID AGENTS GENERIC BRAND REL. COST NAME NAME VALUE methimazole Tapazole $ +propylthiouracil +Propylthiouracil $
7.2 THYROID HORMONES GENERIC BRAND REL. COST NAME NAME VALUE desiccated thyroid Thyroid, Thyroid SPT $ levothyroxine Synthroid, Levoxine $ liothyronine Cytomel $ liotrix Thyrolar $
7.3 ADRENAL HORMONES GENERIC BRAND REL. COST NAME NAME VALUE flucinonide Flucinonide $ fludrocortisone Florinef $ +hydrocortisone +Cortef, Hydrocortone $ +prednisone liquid +Liquid Pred $ +prednisone tablet +Deltasone, Orasone, $ Meticorten +triamcinolone +Aristocort, T-Cort $ +dexamethasone +Decadron $$ +methylprednisolone +Medrol $$ prednisolone syrup Prelone $$$ betamethasone Celestone $$$$ paramethasone Haldrone $$$$
7.4 MISCELLANEOUS HORMONES GENERIC BRAND REL. COST NAME NAME VALUE 7.4.1 ANDROGENS testosterone Testopel $ testosterone propionate Testex $ (inj) nandrolone decanoate Deca-Durabolin $$ fluoxymesterone Halotestin $$$ methyltestosterone Android $$$ methyltestosterone Methyltestosterone, $$$ Testred testosterone, Testoderm $$$ transdermal testosterone, Androderm $$$$ transdermal +danazol +Danocrine $$$$$! oxandrolone Oxandrin $$$$$!
Refer to 11.3 for Estrogens & Progestins +Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ♦Dosage reduction may be required in the elderly.
7.4.2 OVULATORY STIMULANTS +clomiphene +Clomid, Serophene $$$$$! menotropin (inj) Humegon, Pergonal $$$$$!!!!! urofollitropin (inj) Fertinex, Metrodin $$$$$!!!!!
7.4.3 MISCELLANEOUS HORMONES lypressin Diapid $ calcifediol Calderol $$ calcitiol Rocaltrol $$ calcitonin-salmon Miacalcin $$$ nasal spray corticotropin Acthar $$$ finasteride Proscar $$$ aminoglutethimide Cytadren $$$$ cabergoline Dostinex $$$$ +calcitonin-salmon (inj) +Miacalcin $$$$$! desmopressin soln/spray DDAVP Soln/Spray $$$$$! desmopressin tabs DDAVP $$$$$! dihydrotachysterol Hytakerol, DHT $$$$$! etidronate Didronel $$$$$! pergolide Permax $$$$$! tiludronate Skelid $$$$$! vasopressin (inj) Pitressin $$$$$!!! nafarelin acetate Synarel $$$$$!!!!! alglucerase (inj) Ceredase $$$$$!!!!!! octreotide (inj) Sandostatin $$$$$!!!!!!
7.4.4 GONADOTROPIN & RELATED AGENTS chorionic Profasi HP $$$$$! gonadotropin (inj)
7.5 DIABETES THERAPY GENERIC BRAND REL. COST NAME NAME VALUE 7.5.1 INSULIN THERAPY insulin (beef/pork) (inj) Lilly Iletin $$ insulin (human) (inj) Humulin, Novolin $$ insulin (beef/pork) (inj) Novo-Nordisk $$$ insulin lispro (inj) Humalog $$$
7.5.2 ORAL HYPOGLYCEMIC AGENTS FIRST GENERATION +acetohexamide +Dymelor $ +chlorpropamide +Diabinese $ +tolbutamide +Tolinase $ +tolazamide +Orinase $
SECOND GENERATION +glipizide +Glucotrol $ glipizide ER Glucotrol XL $ +glyburide +Micronase, Glynase, $$ DiaBeta
OTHER glimepiride Amaryl $ acarbose Precose $$ metformin Glucophage $$ troglitazone Rezulin $$$$$
7.5.3 GLUCOSE ELEVATING AGENTS Glucagon (inj) Glucagon Emergency $$$$$!!!!! Kit, Glucagon for Inj
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ♦Dosage reduction may be required in the elderly.
MERCK & CO., INC., ET AL. 187
156 Decision and Order
APPENDIX A
7.5.4 INSULIN SYRINGES insulin syringes BD Ass't Syrin $ insulin syringes BD Syringes 28 $ insulin syringes BD Syringes 29 $ insulin syringes BD Ins Syr 30G $ insulin syringes Lancets BD Ult $ insulin syringes Lancets Monole $ insulin syringes Monoject Ass't $ insulin syringes Monoject Syr 2 $ insulin syringes Needles and Sy $ insulin syringes Sure-Dose 28G1 $ insulin syringes Sure-Dose 29G1 $ insulin syringes Terumo Ins Syr $ insulin syringes NovoFine Ins N $$
7.5.5 BLOOD GLUCOSE MONITORING STRIPS blood glucose Chemstrip K $ test strips (test strip) blood glucose Lancets $ test strips blood glucose Soft Touch $ test strips blood glucose Accu-Chek B1101 $$$ test strips blood glucose Chemstrip BG $$$ test strips (test strip) blood glucose Exactech $$$ test strips blood glucose Glucofilm $$$ test strips blood glucose Glucometer ELI $$$ test strips blood glucose Glucometer ENC $$$ test strips blood glucose Glucostix $$$ test strips blood glucose One Touch $$$ test strips blood glucose Prestige Test $$$ test strips blood glucose Surestep $$$ test strips blood glucose Tracer BG $$$ test strips blood glucose Glucoscan $$$$ test strips blood glucose Medisense 2 $$$$ test strips blood glucose Precision QID $$$$ test strips
7.5.5 BLOOD GLUCOSE MONITORING METERS blood glucose Accu-Chek Meter $ monitoring meters blood glucose Exactech Meter $ monitoring meters blood glucose Glucometer II $ monitoring meters blood glucose One Touch II $ monitoring meters blood glucose One Touch Prof $ monitoring meters blood glucose Precision Meter $ monitoring meters
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
8. GASTROENTEROLOGY
8.1 ULCER THERAPY GENERIC BRAND REL. COST NAME NAME VALUE
8.1.1 H2 ANTAGONISTS ↓+cimetidine +Tagamet $ +nizatidine Axid $$$ ↓+ranitidine +Zantac $$$ ↓+famotidine Pepcid $$$$
8.1.2 PROSTAGLANDINS misoprostol Cytotec $$
8.1.3 OTHER ULCER THERAPY +sucralfate +Carafate $$$ bismuth/metronidazole/ Tritec $$$$ tetracycline ranitidine bismuth Helidac $$$$ citrate
8.1.4 PROTON PUMP INHIBITORS lansoprazole Prevacid $$$$ omeprazole Prilosec $$$$$
8.2 ANTIDIARRHEALS & ANTISPASMODICS GENERIC BRAND REL. COST NAME NAME VALUE
8.2.1 ANTIDIARRHEALS +paregoric +Paregoric USP, $ Kaodene w/Paregoric +diphenoxylate/atropine +Lomotil, Logen $$ opium preparations Opium Tincture $$$$$!
8.2.2 ANTISPASMODICS ▲+dicyclomine +Bentyl $ +glycopyrrolate +Robinul $ ▲hyoscyamine caps Levsinax $ ▲hyoscyamine oral Levbid, Gastrosed $ ▲hyoscyamine SL Levsin $ methscopolamine Pamine $ ▲+propantheline +Pro-Banthine $ clidinium Quarzan $$
8.2.3 COMBINATION ANTICHOLINERGICS ▲+atropine +Donnatal, $ w/phenobarbital/ Barbidonna, scopolamine/ Chardonna hyoscyamine +chlordiazepoxide/ +Librax $ clidinium
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
Decision and Order 127 F.T.C.
APPENDIX A
8.3 MISCELLANEOUS GASTROINTESTINAL AGENTS GENERIC BRAND REL. COST NAME NAME VALUE 8.3.1 BILE ACIDS chenodiol — Chenix $$$$ ursodiol Actigall $$$$$!
8.3.2 DIGESTIVE ENZYMES pancrelipase Pancrease $$$ pancrelipase Ultrase $$$ pancreatin Creon $$$$$ pancrelipase Pancrease MT $$$$$! pancrelipase Ultrase MT $$$$$!!!
8.3.3 MISCELLANEOUS GASTROINTESTINAL AGENTS hydrocortisone 1% Proctocort $ +metoclopramide +Reglan $ +sulfasalazine +Azulfidine $ hydrocortisone acetate Hemorrhoidal HC $$ +lactulose +Constulose, +Enulose $$ cisapride Propulsid $$$ hydrocortisone foam Cortifoam $$$ olsalazine Dipentum $$$ pramoxine/HC ProctoFoam-HC $$$ cromolyn oral Gastrocrom $$$$$ hydrocortisone enema Cortenema $$$$$! mesalamine Asacol, Pentasa, $$$$$! Rowasa
8.3.4 ANTIEMETICS +meclizine +Antivert $ +promethazine +Phenergan $ scopolamine Transderm-Scop $$ +trimethobenzamide +Tigan $$ +prochlorperazine +Compazine $$$$ +trimethobenzamide +Tigan $$$$ (supp) +trimethobenzamide +Tigan $$$$$! (inj) +prochlorperazine +Compazine $$$$$!! (supp) +promethazine (supp) +Phenergan $$$$$!! granisetron Kytril $$$$$!!!!! ondansetron Zofran $$$$$!!!!!
8.3.5 BOWEL EVACUANTS electrolyte solution Colyte, GoLYTELY $$$$$! NuLYTELY
9. BIOTECHNOLOGY DRUGS GENERIC BRAND REL. COST NAME NAME VALUE 9.1.1 ERYTHROID STIMULANTS erythropoietin (inj) Procrit, Epogen $$$$$!!!!!
9.1.2 MYELOID STIMULANTS filgrastim (inj) Neupogen $$$$$!!!!! sargramostim (inj) Leukine $$$$$!!!!!
9.1.3 INTERFERONS alpha 2a (inj) Roferon A $$$$$!!!!! alpha 2b (inj) Intron A $$$$$!!!!! alpha n3 (inj) Alferon N $$$$$!!!!! beta 1a (inj) Avonex $$$$$!!!!! beta 1b (inj) Betaseron $$$$$!!!!! gamma 1b (inj) Actimmune $$$$$!!!!!
9.1.4 GROWTH HORMONES somatropin (inj) Genotropin, Humatrope, $$$$$!!!!! Nutropin, Nutropin AQ, Protropin
10. MUSCULOSKELETAL & RHEUMATOLOGY GENERIC BRAND REL. COST NAME NAME VALUE 10.1 NSAIDs +fenoprofen +Nalfon $ +ibuprofen +Motrin, Rufen $ +indomethacin +Indocin $ +meclofenamate +Meclomen $ +naproxen +Naprosyn $ +naproxen sod +Anaprox, Anaprox DS., $ Naprelan phenylbutazone Butazolidin $ +piroxicam +Feldene $ +sulindac +Clinoril $ +diclofenac +Voltaren $$ +flurbiprofen +Ansaid $$ +ibuprofen suspension +Children's Advil, $$ Children's Motrin +indomethacin SR +Indocin SR $$ +tolmetin +Tolectin $$ +etodolac +Lodine $$$ +ketoprofen +Orudis $$$ +ketoprofen SR +Oruvail $$$ nabumetone Relafen $$$ oxaprozin Daypro $$$ diclofenac potassium Cataflam $$$$$ +ketorolac +Toradol $$$$$ ketorolac (inj) Toradol $$$$$!!!!!
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
— 19
MERCK & CO., INC., ET AL.
Decision and Order APPENDIX A
10.1.2 SALICYLATES salicylamide Saleto-D $ +salsalate +Salflex $ asa sustained release Zorprin $$ +choline magnesium +Trilisate $$ salicylate +diflunisal +Dolobid $$$ salicylate salts Arthropan $$$
10.2 GOUT THERAPY GENERIC BRAND REL. COST NAME NAME VALUE *allopurinol *Zyloprim $ *colchicine *Colchicine $ *probenecid *Benemid $ *probenecid *Col Benemid $ w/colchicine
10.3 OTHER RHEUMATOLOGICALS GENERIC BRAND REL. COST NAME NAME VALUE 10.3.1 CORTICOSTEROIDS *hydrocortisone *Cortef, Hydrocortone $ *prednisone *Orasone, Deltasone $ *triamcinolone *Aristocort $ *dexamethasone *Decadron $$ *methylprednisolone *Medrol $$ *prednisone liquid *Liquid Pred $$ prednisolone syrup Prelone $$$ betamethasone Celestone $$$$ paramethasone Haldrone $$$$
10.3.2 MISCELLANEOUS RHEUMATOLOGICAL AGENTS *sulfasalazine *Azulfidine $ *methotrexate *Rheumatrex, $$ Methotrexate auranofin Ridaura $$$ *azathioprine *Imuran $$$ penicillamine Cuprimine $$$ aurothioglucose Solganal $$$$$
10.3.3 MUSCLE RELAXANTS & ANTISPASMODIC THERAPY *+carisoprodol *Soma $ *+chlorzoxazone *Paraflex, $ Parafon Forte DSC *+cyclobenzaprine *Flexeril $ *+diazepam *Valium $ *+methocarbamol *Robaxin $ *+oxybutynin *Ditropan $ *baclofen *Lioresal $$ *metaxalone Skelaxin $$$ chlorphenesin Maolate $$$$ dantrolene Dantrium $$$$ *orphenadrine/ *Norflex $$$$ asa/caffeine
*Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ♦Dosage reduction may be required in the elderly.
10.4 OSTEOPOROSIS THERAPY GENERIC BRAND REL. COST NAME NAME VALUE alendronate Fosamax $$ +calcitonin-salmon +Miacalcin $$$ nasal spray
11. OBSTETRIC & GYNECOLOGY
11.1 ORAL CONTRACEPTIVES & RELATED AGENTS GENERIC BRAND REL. COST NAME NAME VALUE 1st GENERATION, Mono-phasic ethinyl estradiol/ Demulen $ ethynodiol ethinyl estradiol/ Estrostep FE $ norethindrone ethinyl estradiol, Genora 1/35 $ norethindrone ethinyl estradiol, Loestrin $ norethindrone *levonorgestrel/ Alesse, Levlen, $ ethinyl estradiol Levora, Nordette *norethindrone/ Brevicon, Modicon, $ ethinyl estradiol Ovcon *norethindrone/ N.E.E., Nelova, $ ethinyl estradiol Ortho-Novum *norethindrone/ Norinyl $ mestranol norgestrel/ Lo/Ovral $$ ethinyl estradiol norgestrel/ Ovral $$ ethinyl estradiol
1st GENERATION, Bi-phasic *norethindrone/ Jenest, Nelova, $ ethinyl estradiol Ortho-Novum 10/11
1st GENERATION, Tri-phasic levonorgestrel/ Tri-Levlen, Triphasil $ ethinyl estradiol norethindrone/ Tri-Norinyl, $ ethinyl estradiol Ortho-Novum 777
2nd GENERATION, Mono-phasic desogestrel/ Desogen, Ortho-Cept $ ethinyl estradiol norgestimate/ Ortho-Cyclen $ ethinyl estradiol
2nd GENERATION, Tri-phasic norgestimate/ Ortho Tri-Cyclen $ ethinyl estradiol
*Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ♦Dosage reduction may be required in the elderly.
Decision and Order 127 F.T.C.
APPENDIX A
11.1.2 PROGESTIN ONLY Norethindrone Micronor, Nor QD $ Norgestrel Ovrette $$
11.2 OXYTOCICS GENERIC BRAND REL. COST NAME NAME VALUE methylergonovine Methergine $$$ oxytocin spray Syntocinon $$$$$!
11.3 ESTROGENS & PROGESTINS GENERIC BRAND REL. COST NAME NAME VALUE 11.3.1 PROGESTINS hydroxyprogesterone Delalutin $ +medroxyprogesterone +Provera $ norethindrone Micronor, Nor QD $ norethindrone acetate Norlutate $ medroxyprogesterone Depo-Provera $$ acetate norethindrone acetate Aygestin, Norlutin $$ norgestrel Ovrette $$ +progesterone inj. +Gesterol 50 $$$ progesterone Progestcrone supp $$$$$! vaginal suppos progesterone gel Crinone $$$$$!!
11.3.2 ESTROGENS conjugated estrogens Premarin $ esterified estrogens Menest, Estratab $ esterified estrogens/ Estratest $ methyltestosterone +estradiol +Estrace $ estradiol transdermal Climara, Vivelle, $ Estraderm, Alora, FemPatch +estropipate +Ogen, Ortho-Est $ ethinyl estradiol Estinyl $ chlorotrianisene Tace $$ conj estrogen Premarin $$ vaginal cream dienestrol cream Ortho Dienestrol $$ estradiol vaginal ring Estring $$ quinestrol Estrovis $$$$
11.3.3 ESTROGEN COMBINATIONS conjugated estrogens/ Premphase, Prempro $ medroxyprogesterone
11.4 MISCELLANEOUS OB/GYN GENERIC BRAND REL. COST NAME NAME VALUE 11.4.1 DRUGS TO TREAT INFERTILITY/IVF AGENTS chorionic gonadotropin Profasi HP, APL $$$$$! (inj) +clomiphene +Clomid, Serophene $$$$$! leuprolide (inj) Lupron $$$$$!!!!! menotropin (inj) Humegon, Pergonal $$$$$!!!!! urofollitropin (inj) Fertinex, Metrodin $$$$$!!!!! Amp 2
11.4.2 VAGINAL CLEANSER/ANTI-INFECTIVES +triple sulfa +Sultrin, Trysol $ acetic acid/oxyquinoline Aci-Jel $$$ ricinoleic/glycerin +sulfanilamide vaginal +AVC $$$ metronidazole MetroGel-Vag $$$$ vaginal gel clindamycin Cleocin Vag $$$$$
11.4.3 VAGINAL ANTIFUNGALS butaconazole Femstat $ +nystatin vaginal +Nystatin, Mycostatin $ tioconazole Vagistat-1 $ tioconazole ointment Vagistat $ clotrimazole Mycelex-G $$ terconazole Terazol $$$$$ fluconazole oral Diflucan $$$$$! miconazole Monistat 3, $$$$$! Monistat Dual Pak
11.4.4 SPECIALIZED OB/GYN DRUGS +isoxsuprine +Vasodilan $ terbutaline Brethine, Bricanyl $$ nafarelin acetate Synarel $$$$$!!!!
12. OPHTHALMOLOGY
12.1 BETA-BLOCKERS GENERIC BRAND REL. COST NAME NAME VALUE metipranolol OptiPranolol $ betaxolol Betoptic, Betoptic S $$ +levobunolol +Betagan $$ timolol hemihydrate Betimol $$ timolol maleate Timoptic XE $$ +timolol ophth +Timoptic $$
12.2 CHOLINESTERASE INHIBITOR MIOTICS GENERIC BRAND REL. COST NAME NAME VALUE echothiophate Phospholine Iodide $
+Use generic; brand name listed for reference only. ^Use in the elderly is associated with increased risk. !Dosage reduction may be required in the elderly.
+Use generic; brand name listed for reference only. ^Use in the elderly is associated with increased risk. !Dosage reduction may be required in the elderly.
MERCK & CO., INC., ET AL.
Decision and Order APPENDIX A
12.3 DIRECT ACTING MIOTICS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | echothiophate | Phospholine Iodide | $ | | physostigmine | Isopto Eserine | $ | | +pilocarpine | +Pilocar, Ocusert Pilo-20, Pilagan | $ | | pilocarpine gel | Pilopine HS | $$$ | | acetylcholine | Miochol | $$$$$!! | | carbachol | Miostat | $$$$$!!!!! |
12.4 OTHER GLAUCOMA DRUGS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | carbachol | Isopto Carbachol | $$ | | demecarium | Humorsol | $$ | | dorzolamide | Trusopt | $$ | | epinephrine/ pilocarpine | P1E1, P2E1, P3E1 P4E1, P6E1 | $$ | | latanoprost | Xalatan | $$$ |
12.5 ORAL DRUGS FOR GLAUCOMA | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +acetazolamide | +Diamox | $ | | +methazolamide | +Neptazane | $ | | dichlorphenamide | Daranide | $$ |
12.6 CYCLOPLEGIC MYDRIATICS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +atropine sulfate | +Isopto Atropine, Atropine Sulfate S.O.P. | $ | | +cyclopentolate | +Cyclogyl | $ | | +dipivefrin | +Propine | $ | | homatropine | Isopto Homatropine | $ | | phenylephrine | AK-Nefrin | $ | | scopolamine | Isopto Hyoscine | $ | | +tropicamide | +Mydriacyl | $ | | epinephrine | Epinephrine | $$$ |
12.7 NON-STEROIDAL ANTI-INFLAMMATORY AGENTS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | ketorolac | Acular | $ | | +flurbiprofen | +Ocufen | $$ | | suprofen | Profenal | $$ | | diclofenac | Voltaren | $$$ |
+ Use generic; brand name listed for reference only. ▲ Use in the elderly is associated with increased risk. ↓ Dosage reduction may be required in the elderly.
12.8 VASOCONSTRICTOR DECONGESTANTS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +naphazoline/antazoline | +Albalon | $ | | phenylephrine | Neo-Synephrine | $ |
12.9 ANTIBIOTICS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +bacitracin | +Bacitracin | $ | | bacitracin/neosporin/ polymyxin B/HC | AK-Spor HC | $ | | +erythromycin | +Ilotycin | $ | | +gentamicin | +Garamycin, Gentacidin | $ | | +neomycin/polymyxin/ bacitracin ointment | +Neosporin | $ | | +tobramycin | +Tobrex | $ | | zinc sulfate | Eye-Sed | $ | | polymyxin B/ trimethoprim | Polytrim | $$ | | ciprofloxacin | Ciloxan | $$$ | | norfloxacin | Chibroxin | $$$ | | ofloxacin | Ocuflox | $$$ | | +chloramphenicol | +Chloroptic S.O.P. | $$$$ | | natamycin | Natacyn | $$$$ | | polymyxin B | Polymyxin B | $$$$$! | | chlortetracycline | Aureomycin | $$$$$!! | | polymyxin B | Aerosporin | $$$$$!! |
12.10 SULFONAMIDES | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +sodium sulfacetamide | +Bleph-10, Sulamyd, AK-Sulf | $ | | sulfacetamide/ phenylephrine | Vasosulf | $ | | sulfisoxazole | Gantrisin | $$ |
12.11 STEROIDS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +dexamethasone | +Decadron, Maxidex | $ | | +prednisolone sodium phosphate | +Inflamase, Inflamase Forte | $ | | +fluorometholone | +FML, FML Forte, FML SOP | $$ | | medrysone | HMS | $$ | | +prednisolone | +Pred-Mild, Pred-Forte | $$ | | rimexolone | Vexol | $$ |
+ Use generic; brand name listed for reference only. ▲ Use in the elderly is associated with increased risk. ↓ Dosage reduction may be required in the elderly.
Decision and Order 127 F.T.C.
APPENDIX A
12.12 STEROID-ANTIBIOTIC COMBINATIONS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +neomycin/polymyxin/ dexamethasone | +Maxitrol, Dexacidin | $ | | +neomycin/bacitracin/ polymyxin/HC | +Cortisporin | $$ | | +neomycin/ dexamethasone | +Neo-Decadron | $$ | | neomycin/polymyxin/ prednisolone | Poly-Pred | $$$ | | tobramycin/ dexamethasone | TobraDex | $$$ |
12.13 STEROID-SULFONAMIDE COMBINATIONS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +sulfacetamide/ prednisolone | +Vasocidin | $$ | | sulfacetamide/ prednisolone | Blephamide | $$$ | | sulfacetamide/ prednisolone | Metimyd | $$$$$! |
12.14 SYMPATHOMIMETICS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | +dipivefrin | +Propine | $ | | brimonidine | Alphagan | $$ | | apraclonidine | Iopidine | $$$ | | epinephrine borate | Eppy/N | $$$ | | epinephrine HCl | Epifrin | $$$ |
12.15 MISCELLANEOUS OPHTHALMOLOGICS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | proparacaine | AK-Taine | $ | | tetracaine | Pontocaine | $ | | silver nitrate | Silver Nitrate | $$ | | artificial tear insert | Lacrisert | $$$ | | cromolyn | Crolom | $$$ | | levocabastine | Livostin | $$$ | | lodaxamide | Alomide | $$$ | | olopatadine | Patanol | $$$$$! | | chymotrypsin | Catarase | $$$$$!!!!! |
+ Use generic; brand name listed for reference only. ▲ Use in the elderly is associated with increased risk. ↓ Dosage reduction may be required in the elderly.
12.16 ANTIVIRALS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | idoxuridine | Herplex | $ | | vidarabine | Vira-A | $$$$ | | +trifluridine | +Viroptic | $$$$$ |
13. RESPIRATORY, ALLERGY, COUGH & COLD
13.1 ANTIHISTAMINE & ANTIALLERGENIC AGENTS | GENERIC NAME | BRAND NAME | REL. COST VALUE | | 13.1.1 ANTIHISTAMINES | | | | carbinoxamine | Clistin | $ | | ▲clemastine 2.68 | Tavist 2.68 | $ | | ▲+cyproheptadine | +Periactin | $ | | ▲+diphenhydramine | +Benadryl | $ | | ▲+hydroxyzine HCl | +Atarax | $ | | ▲+hydroxyzine pamoate | +Vistaril | $ | | ▲+promethazine | +Phenergan | $ | | ▲+tripelennamine | +PBZ, PBZ SR | $ | | azatadine | Optimine | $$ | | azelastine | Astelin | $$ | | cetirizine | Zyrtec, Zyrtec Syrup | $$ | | ▲clemastine syrup | Tavist suspension | $$ | | ▲dexchlorpheniramine | Polaramine | $$ | | fexofenadine | Allegra | $$ | | loratadine | Claritin, Claritin Reditabs | $$ |
| 13.1.2 ADRENERGICS | | | | +epinephrine (inj) | +Epinephrine | $$$ | | +epinephrine (inj) | +EpiPen, +EpiPen Jr. | $$$$$!! |
| 13.1.3 CORTICOSTEROIDS | | | | +hydrocortisone | +Cortef, Hydrocortone | $ | | +prednisone | +Deltasone, Orasone | $ | | +prednisone liquid | +Liquid Pred | $ | | +triamcinolone | +Aristocort | $ | | +dexamethasone | +Decadron | $$ | | +methylprednisolone | +Medrol | $$ | | prednisolone syrup | Prelone | $$$ | | betamethasone | Celestone | $$$$ |
13.2 COUGH & COLD THERAPY | GENERIC NAME | BRAND NAME | REL. COST VALUE | | 13.2.1 ANTITUSSIVE COMBINATIONS | | | | brompheniramine/ pseudoephedrine/ dextromethorphan | Myphetane DX | $ |
+ Use generic; brand name listed for reference only. ▲ Use in the elderly is associated with increased risk. ↓ Dosage reduction may be required in the elderly.
MERCK & CO., INC., ET AL.
Decision and Order APPENDIX A
+codeine/guaifenesin +Mytussin AC, S Robitussin AC ▲+codeine/ +Promethazine S phenylephrine/ VC/Cod promethazine ▲+promethazine/codeine +Phenergan/Co $ +pseudoephedrine/ +Nuco-Tuss Exp $ codeine/guaifenesin Robitussin DAC ▲+brompheniramine/ +Bromanate DC, SS codeine/ Poly-Histine CS phenylpropanolamine ▲+brompheniramine/ +Delhistine DM SS dextromethorphan/ Poly-Histine DM phenylpropanolamine ▲+chlorpheniramine/ +Histinex HC, SS phenylephrine/ Histussin HC hydrocodone codeine Codeine Phosphate Soln SS +dextromethorphan/ +Guaifenex DM, SS guaifenesin +homatropine/ +Hydromet, Hycodan SS hydrocodone ▲hydrocodone/ Tussionex SS chlorpheniramine hydrocodone/ Deconamine CX SS pseudoephedrine/ guaifenesin +benzonatate +Tessalon Perle SSS +dextromethorphan/ Humibid DM SSS guaifenesin +hydrocodone/ +Codamine, Hycomine SSS phenylpropanolamine +Hycomine Pediatric ▲+pseudoephedrine/ +Rondec DM SSS carbinoxamine/ dextromethorphan pseudoephedrine/ Histussin D SSS hydrocodone
13.2.2 EXPECTORANT COMBINATIONS +guaifenesin/ +Phenylfenesin LA S phenylpropanolamine potassium iodide SSKI S +guaifenesin +Humibid LA SS +guaifenesin/ +Exgest LA SS phenylpropanolamine +Entex LA +phenylpropanolamine/ +Entex SS guaifenesin/ phenylephrine +pseudoephedrine/ +Duratuss SS guaifenesin +pseudoephedrine/ +Guaifed SS guaifenesin SR pseudoephedrine/ Syn Rx SSS giaofemesom/ guaifenesin
13.2.3 DECONGESTANT/ANTIHISTAMINES chlorpheniramine/ Extendryl SR $ phenylpropanolamine/ methscopolamine ▲+chlorpheniramine/ +Naldelate $ phenyltoloxamine/ phenylephrine/ phenylpropanolamine
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
▲+promethazine/ +Phenergan VC S phenylephrine acrivastine/ Semprex D SS pseudoephedrine ▲+brompheniramine/ +Bromfed Caps SS pseudoephedrine phenylpropanolamine/ Duaducin SS chlorpheniramine/apap ▲phenylpropanolamine/ Nolamine SS chlorpheniramine/ phenylephrine ▲+phenylpropanolamine/ +Poly-Histine-D, SS phenyltoloxamine/ Poly-Histine-D Ped pyrilamine/ pheniramine pseudoephedrine Novafed SS ▲+pseudoephedrine/ +Rondec SS carbinoxamine ▲+pseudoephedrine/ +Deconamine SR SS chlorpheniramine ▲azatadine/ Trinalin SSS pseudoephedrine loratadine/ Claritin D SSS pseudoephedrine
13.3 PULMONARY AGENTS GENERIC BRAND REL. COST NAME NAME VALUE 13.3.1 XANTHINES +aminophylline +Aminophylline $ oxtriphylline Choledyl $ theophylline anhydrous Bronkodyl, $ Elixophyllin, Theoclear, Aerolate, Theolair theophylline Slo-Phyllin, Theolair, S immediate release Quinbron T +theophylline +Aerolate, Slo-Phyllin S timed release Gyrocaps, Quibron T, Slo-bid Gyrocaps, Theo-Dur, Theochron, Theolair SR, T-Phyl, Uniphyl
13.3.2 BETA AGONISTS ORAL +albuterol tabs +Proventil, Ventolin $ albuterol Proventil Repetabs, SS Volmax ER +albuterol syrup +Proventil, Ventolin SS +metaproterenol +Metaprel, Alupent SS terbutaline Brethine, Bricanyl SS +ephedrine +Ephedrine SSSS
13.3.3 BETA AGONISTS INHALERS +albuterol +Proventil, Ventolin $ for inhalation epinephrine Epinephrine Mist $ +metaproterenol 5% +Metaprel, Alupent $ soln for inhalation +metaproterenol soln +Metaprel $ 0.4%, 0.6% for inhalation
+Use generic; brand name listed for reference only. ▲Use in the elderly is associated with increased risk. ↓Dosage reduction may be required in the elderly.
Decision and Order 127 F.T.C.
APPENDIX A
albuterol Ventolin Rotacaps SS +albuterol soln +Proventil, Ventolin SS bitolterol Tornalate SS isoproterenol Esuprel Mistometer SS isoproterenol/ Duo-Medihaler SS - phenylephrine metaproterenol aerosol Alupent SS pirbuterol Maxair SS +isoetharine +Bronkosol, SSS Arm-a-med salmeterol Serevent SSS
13.3.4 INHALED CORTICOSTEROIDS beclomethasone Beclovent, Vanceril SS budesonide Pulmicort SS beclomethasone Vanceril DS SSS fluticasone Flovent SSS triamcinolone Azmacort SSS dexamethasone Dexacort Respihaler SSSS flunisolide Aerobid, AeroBid M SSSS
13.3.5 INTRANASAL STEROIDS beclomethasone Beconase AQ, SS Vancenase AQ, Vancenase AQ DS beclomethasone Vancenase SS pockethaler budesonide Rhinocort SS flunisolide Nasalide SS fluticasone Flonase SS dexamethasone Dexacort Turbinaire SSS triamcinolone Nasacort SSS triamcinolone acetonide Nasacort AQ SSS
13.3.6 MISCELLANEOUS PULMONARY AGENTS ipratropium/albuterol Combivent SS nedocromil Tilade SS zafirlukast Accolate SS atropine (inj) Atropine Auto SSS cromolyn for inhalation Intal, Nasalcrom SSS zileuton Zyflo SSS ipratropium Atrovent inhal SSSSS +acetylcysteine +Mucomyst SSSSS!!!!! dornase alpha Pulmozyme SSSSS!!!!!
14. UROLOGICALS
14.1 CHOLINERGIC STIMULANTS GENERIC BRAND REL. COST NAME NAME VALUE +bethanechol +Urecholine $
14.2 ANTICHOLINERGICS & ANTISPASMODICS GENERIC BRAND REL. COST NAME NAME VALUE +dicyclomine +Bentyl $
+ Use generic; brand name listed for reference only. ^ Use in the elderly is associated with increased risk. ↓ Dosage reduction may be required in the elderly.
ahyoscyamine Levsin, Levsin ex, $ Cystospaz +oxybutynin +Ditropan $ +propantheline +Pro-Banthine $ flavoxate Urispas SSSSS
14.3 URINARY ANESTHETICS GENERIC BRAND REL. COST NAME NAME VALUE +phenazopyridine +Pyridium $
14.4 MISCELLANEOUS UROLOGICALS GENERIC BRAND REL. COST NAME NAME VALUE doxazosin Cardura SS methenamine/phenyl- Urised SS salicylate/atropine/ hyoscyamine/benzoic acid/methylene blue terazosin Hytrin SS finasteride Proscar SSS citric acid/ Renacidin SSSS d-gluconic acid pentosan polysulfate/ Elmiron SSSSS sodium alprostadil injection Caverject SSSSS! alprostadil (supp) Muse, Edex SSSSS!!!
15. VITAMINS, HEMATINICS & ELECTROLYTES
15.1 VITAMINS & HEMATINICS GENERIC BRAND REL. COST NAME NAME VALUE +ADC vit w/fl +Vitamins A, D, C $ with fluoride +ergocalciferol +Deltalin, Calciferol $ ferrous fumarate Feostat $ ferrous gluconate Simron $ ferrous sulfate Fer-in-Sol $ fluorides Pediaflor Drops $ +folic acid +Folvite $ +MVI w/fl +Tri-Vi-Flor, $ +Poly-Vi-Flor MVL prenatal Prenate Ultra, Materna $ nicotinic acid Niacin $ polysaccharide iron Hytinic $ complex +sod fluoride +Luride $ +vitamin A +Aquasol-A $ +vitamin B12 +Cyanocobalamin $ beta-carotene Solatene SS calcifediol Calderol SS
+ Use generic; brand name listed for reference only. ^ Use in the elderly is associated with increased risk. ↓ Dosage reduction may be required in the elderly.
MERCK & CO., INC., ET AL.
Decision and Order APPENDIX A
calcitriol Rocaltrol $$ cyanocobalamin Nascobal $$ dihydrotachysterol Hytakerol $$$$$! iron dextran InFeD $$$$$!
15.2 COAGULATION THERAPY GENERIC BRAND REL. COST NAME NAME VALUE 15.2.1 ANTICOAGULANTS anisindione Miradon $ dicumarol Dicumarol $ +warfarin +Coumadin $
15.2.2 ANTIPLATELET DRUGS +dipyridamole +Persantine $ ticlopidine Ticlid $$$$
15.2.3 HEPARIN +heparin (inj) +Heparin $$$
15.2.4 VITAMIN K phytonadione Mephyton $$$
15.2.5 HEMOSTATICS aminocaproic acid Amicar $$
15.2.6 MISCELLANEOUS COAGULATION AGENTS +pentoxifylline +Trental $$
15.3 ELECTROLYTES GENERIC BRAND REL. COST NAME NAME VALUE +effervescent potassium +Klor-Con/EF $ +KCl 8 mEq, SR cap +Micro-K 8 mEq $ +KCl 8 mEq, SR tab +Slow K $ +KCl 10 mEq, SR cap +Micro-K 10 mEq $ +KCl 10 mEq, SR tab +Kaon Cl-10, K-Tab, $ +K-Dur +KCl 10%, liquid +Kayciel Elixir $ potassium citrate Urocit-K $ +potassium gluconate +Kaon $ liquid +powdered potassium +K-Lor, Klor-Con $
15.4 MISCELLANEOUS VITAMINS, HEMATINICS & ELECTROLYTES GENERIC BRAND REL. COST NAME NAME VALUE ammonium chloride $ penicillamine Cuprimine $$$ citrate salts Polycitra-K $$$$ cellulose Calcibind $$$$$! +sodium polystyrene +Kayexalate $$$$$! sulfonate deferoxamine Desferal $$$$$!! succimer Chemet $$$$$!! dimercaprol BAL in Oil $$$$$!!!!! +Use generic; brand name listed for reference only. ▲ Use in the elderly is associated with increased risk. ↓ Dosage reduction may be required in the elderly.
16. DIAGNOSTICS & MISCELLANEOUS
16.1 MISCELLANEOUS AGENTS GENERIC BRAND REL. COST NAME NAME VALUE +disulfiram +Antabuse $ levocarnitine Carnitor $$$$ pilocarpine, oral Salagen $$$$ midodrine ProAmatine $$$$$!
16.2 SMOKING DETERRENTS GENERIC BRAND REL. COST NAME NAME VALUE bupropion Zyban $$$ nicotine nasal spray Nicotrol NS $$$$$ nicotine polacrilex Nicorette gum, $$$$$! Nicorette DS
16.4 MISCELLANEOUS AGENTS GENERIC BRAND REL. COST NAME NAME VALUE alpha 1-proteinase Prolastin $$$$$!!!!! inhibitor (human)
16.6 IRRIGATION SOLUTIONS GENERIC BRAND REL. COST NAME NAME VALUE acetic acid Acetic Acid Irrigation $$$$$!!!!
16.7 ENZYMES GENERIC BRAND REL. COST NAME NAME VALUE hyaluronidase (inj) Wydase $$$$$!
16.9 LOCAL ANESTHETICS GENERIC BRAND REL. COST NAME NAME VALUE lidocaine (top) Lidocaine $
+Use generic; brand name listed for reference only. ▲ Use in the elderly is associated with increased risk. ↓ Dosage reduction may be required in the elderly.
Decision and Order 127 F.T.C.
APPENDIX A
INDEX A acarbose, 17 Accolate, 25 Accu-Chek B1101, 18 Accu-Chek Meter, 18 Accupril, 12 Accutane, 15 ACE Inhibitors, 12 acebutolol, 12 Acetasol, 16 Acetasol HC, 16 acetazolamide, 22 acetic acid, 16, 26 Acetic Acid Irrigation, 26 acetic acid w/HC, 16 acetic acid/al acetate, 16 acetic acid/oxyquinoline ricineoleic/glycerin, 21 acetohexamide, 17 acetohydroxamic acid, 6 acetophenazine, 10 acetylcholine, 22 acetylcysteine, 25 Achromycin, 5 Aci-Jel, 21 Aclovate, 14 acrivastine/ pseudoephedrine, 24 Acthar, 17 Actigall, 19 Actimmune, 19 Actinex, 16 Acular, 22 acyclovir, 6 acyclovir ointment, 15 Adalat, 12 Adalat CC, 12 adapalene, 15 Adapin, 10 ADC vit w/fl, 25 Adiopost, 10 Adjunctive Agents, 7 Adrenal Hormones, 17 Adrenergic Antagonists & Related Drugs, 12 Adrenergics, 23 Adrucil, 7 Aerobid, 25 AeroBid M, 25 Aerolate, 24 Aerosporin, 22 Agents for Pheochromocytoma, 12 AK-Spor HC, 22 AK-Taine, 23 Akineton, 9 AK-Nefrin, 22 AK-Sulf, 22 Albalon, 22 albuterol, 24, 25 albuterol for inhalation, 24 albuterol soln, 25 albuterol syrup, 24 albuterol tabs, 24 alclometasone dipropionate 0.05% cream, ointment, 14 Aldactazide, 12 Aldactone, 12 Aldara, 16 Aldomet, 12 Aldoril, 13 alendronate, 20 Alesse, 20 Alferon N, 19 alglucerase (inj), 17 Alkeran, 7 Alkylating Agents, 7 Allegra, 23 allopurinol, 20 all-trans retinoic acid, tretinoin, 7 Alomide, 23 Alora, 21 alpha 2a (inj), 19 alpha 2b (inj), 19 alpha 1-proteinase inhibitor (human), 26 alpha n3 (inj), 19 Alphagan, 23 alprazolam, 11 alprostadil (supp), 25 alprostadil injection, 25 Altace, 12 altretamine, 7 aluminum chloride, 16 Alupent, 24, 25 amantadine, 6, 9 Amaryl, 17 ambenonium, 10 Ambien, 10 amcinonide .1% cream, lotion, ointment, 13 Amicar, 11, 26 amiloride, 12 amiloride/HCTZ, 12 aminocaproic acid, 11, 26 aminoglutethimide, 17 Aminoglycosides, 7 aminophylline, 24 aminosalicylic acid, 7 amiodarone, 11 amitriptyline, 10 amlodipine, 12 ammonium chloride, 26 amobarbital/ secobarbital, 11 amoxapine, 10 amoxicillin, 5 amoxicillin/clavulanate, 5 Amoxil, 5 Amp 2, 21 amphetamines, 10 ampho B oral susp, 6 amphotericin B, 15 ampicillin 5 Anafranil, 10 Anaprox, 8, 19 Anaprox DS, 8, 19 anastrozole, 7 Ancobon, 6 Androderm, 17 Androgens, 7, 17 Androgens, Estrogens, Hormones & Related Drugs, 7 Android, 17 Angiotensin II Receptor Blockers, 13 anisindione, 11, 26 Ansaid, 8, 19 Anspor, 5 Antabuse, 26 anthralin, 16 Antiandrogens, 7 Antiarrhythmic agents, 11 Antibiotics, 22 Anticholinergics & Antispasmodics, 25 Anticoagulants, 11, 26 Anticonvulsants, 9 Antidepressant Agents, 10 Antidiarrheals, 18 Antidiarrheals & Antispasmodics, 18 Antiemetics, 19 Antiestrogens, 7 Antifungal Agents, 6 Antihistamine & Antiallergic Agents, 23 Antihistamines, 23 Antihypertensive Therapy, 12 Anti-Infectives, 5 Antimalarials, 7 Antimetabolites, 7 Antimith, 6 Antimycobacterials, 7 Antineoplastics & Immunosuppressant Drugs, 7 Antiparasitics, 6 Antiparkinsonism Agents, 9 Antiplatelet Drugs, 11, 26 Antipsoriatic/ Antiseborrheic, 16 Antipsychotics, 10 antipyrine/benzocaine, 16 Antispasmodics, 18 Antithyroid Agents, 17 Antitussive combinations, 23 Antivert, 9, 19 Antivertigo & Antiemetic Drugs, 9 Antivirals, 6, 23 Anusol HC, 14 Anxiolytics, 11 apap/butalbital, 8 apap/butalbital/ caffeine, 8, 9 apap/codeine, 8 apap/oxycodone capsule, 8 apap/oxycodone tablet, 8 APL, 21 apraclonidine, 23 Apresazide, 13 Apresoline, 12 Aquachloral, 10 Aquasol-A, 25 Aquatensen, 12 Aralen, 7 Aralen/Primaquine, 7 Aricept, 9 Arimidex, 7 Aristocort, 14, 17, 20, 23 Arm-a-med, 25 Artane, 9 Arthropan, 8, 20 artificial tear insert, 23 asa/butalbital/caffeine, 8, 9 asa/butalbital/caffeine/ codeine, 8 asa/carisoprodol/ codeine, 10 asa/codeine, 8 asa/dihydrocodeine, 8 asa/orphenadrine, 10 asa sustained release, 8, 20 asa w oxycodone, 8 Asacol, 19 Asendia, 10 Astelin, 23 Atabrine, 7 Atarax, 23 atenolol, 12 Ativan, 11 atorvastatin, 13 atovaquone, 6 Atropine Auto, 25 atropine (inj), 25 atropine sulfate, 22 Atropine Sulfate S.O.P., 22 atropine w/phenobarbital/ scopolamine/ hyoscyamine, 18 Atrovent inhal, 25 Atrovent Nasal Spray, 16 A/T/S, 15 Augmentin, 5 Auralgan, 16 auranofin, 20 Aureomycin, 22 aurothioglucose, 20 Autonomic & CNS Drugs, Neurology & Psych, 8 AVC, 21 Aventyl, 10 Avonex, 19 Axid, 18 Axotal, 8 Aygestin, 21 azatadine, 23 azatadine/ pseudoephedrine, 24 azathioprine, 7, 20 azelaic acid, 15 azelastine, 23 Azelex, 15 azithromycin, 5 Azmacort, 25 AZT, 6 Azulfidine, 5, 19, 20
MERCK & CO., INC., ET AL. 197
156 Decision and Order
APPENDIX A
B B&O Supprettes, 8 Baciguent, 15 bacitracin, 15, 22 Bacitracin, 22 bacitracin/neosporin/ polymyxin B/HC, 22 baclofen, 10, 20 Bactrim, 5 Bactrim DS, 5 Bactroban, 15 BAL in Oil, 26 Banacap HC, 8 Barbidonna, 18 Barbiturates, 11 BD Ass't Syrin, 18 BD Ins Syr 30G, 18 BD Syringes 28, 18 BD Syringes 29, 18 beclomethasone, 16, 25 beclomethasone pockethaler, 16, 25 Beclovent, 25 Beconase AQ, 16, 25 Beepen-VK, 5 Benadryl, 9, 23 benazepril, 12 benazepril/amlodipine, 13 benazepril/HCTZ, 13 bendroflumethiazide, 12 Benemid, 20 Benoquin, 16 Benyl, 18, 25 Benzac, 15 Benzamycin 23, 15 Benzamycin 46, 15 benzonatate, 24 benzoyl peroxide, 15 Benzoyl peroxide, 15 benzoyl peroxide gel, 15 benzoyl peroxide/ erythromycin, 15 benzoyl peroxide/sulfa, 15 benzphetamine, 10 benzthiazide, 12 benztropine, 9 Benzyl Benzoate, 16 benzyl benzoate lotion, 16 bepridil, 12 beta 1a (inj), 19 beta 1b (inj), 19 Beta Agonists Inhalers, 24 Beta Agonists Oral, 24 Beta Blockers, 12, 21 beta-carotene, 25 Betagan, 21 betamethasone, 14, 17, 20, betamethasone dipropionate .05% (augmented) gel, ointment, cream, 13 betamethasone dipropionate .05% ointment, 13 betamethasone dipropionate .1% aerosol, 14 betamethasone dipropionate 0.05% cream, lotion, 14
betamethasone dipropionate 0.05% lotion, 14 betamethasone dipropionate 0.5% (augmented) cream, 13 betamethasone valerate 0.01% cream, 14 betamethasone valerate 0.1% cream, 14 betamethasone valerate 0.1% lotion, 14 betamethasone valerate 0.1% ointment, 14 Betapace, 11 Betaseron, 19 betaxolol, 12, 21 bethanechol, 25 Betimol, 21 Betoptic, 21 Betoptic S, 21 Biaxin, 5 bicalutamide, 7 Bile Acids, 19 Biltricide, 6 Bio-Tab, 5 Biotechnology Drugs, 19 biperiden, 9 bismuth/metronidazole/ tetracycline, 18 bisoprolol, 12 bisoprolol/HCTZ, 13 bitolterol, 25 Bleph-10, 22 Blephamide, 23 Blocadren, 12 Blood Glucose Monitoring Meters, 18 Blood Glucose Monitoring Strips, 18 blood glucose test strips, 18 Bowel Evacuants, 19 BPO/Sulfur, 15 Brethine, 21, 24 Brevicon, 20 Bricanyl, 21, 24 brimonidine, 23 Bromarate DC, 24 Bromfed Caps, 24 bromocriptine mesylate, 9 brompheniramine/ codeine/phenylpropanolamine, 24 brompheniramine/dextromethorphan/phenylpropanolamine, 24 brompheniramine/ pseudoephedrine, 24 brompheniramine/pseudoephedrine/dextromethorphan, 23 Bronkodyl, 24 Bronkosol, 25 Bucladin-S, 9 buclizine, 9 budesonide, 16, 25 bumetanide, 12 Bumex, 12
Buprenex, 8 buprenorphine (inj), 8 bupropion, 10, 26 Burn Therapy, 15 BuSpar, 11 buspirone, 11 busulfan, 7 butaconazole, 21 butalbital/apap, 9 Butazolidin, 19 butorphanol (inj), 8 butorphanol NS, 8 Butyrophenones, 10
C cabergoline, 17 Cafergot, 9 Calan, 12 Calan SR, 12 Calcibind, 26 calcifediol, 17, 25 Calciferol, 25 calcipotriene, 16 calcitonin-salmon (inj), 17 calcitonin-salmon nasal spray, 17, 20 calcitriol, 17, 26 Calcium Channel Blockers, 12 Calderol, 17, 25 Capitol, 16 Capoten, 12 Capozide, 13 captopril, 12 captopril/HCTZ, 13 Carafate, 18 Carbaphems, 5 carbachol, 22 carbamazepine, 9 carbenicillin, 5 carbidopa-levodopa, 9 carbidopa-levodopa CR, 9 carbinoxamine, 23 Cardene, 12 Cardene SR, 12 Cardiac Glycosides, 11 Cardioquin, 11 Cardiovascular, Hypertension & Lipids, 11 Cardizem, 12 Cardizem CD, 12 Cardizem SR, 12 Cardura, 12, 25 carisoprodol, 10, 20 Carritol, 26 carteolol, 12 Cartrol, 12 carvedilol, 12 Casodex, 7 Cataflam, 8, 19 Catapres, 12 Catapres-TTS, 12 Catarase, 23 Caverject, 25 Ceclor, 5 CeeNU, 7 cefaclor, 5 cefadroxil, 5
cefixime, 5 cefpodoxime, 5 cefprozil, 5 Ceftin, 5 cefuroxime axetil, 5 Cefzil, 5 Celestone, 17, 20, 23 CellCept, 7 cellulose, 26 Celontin, 9 cephalexin, 5 Cephalosporins, 5 cephradine, 5 Ceredase, 17 Cerumenex, 16 cetirizine, 23 Chardonna, 18 Chemet, 26 Chemstrip BG (test strip), 18 Chemstrip K (test strip), 18 Chenix, 19 chenodiol, 19 Chibroxin, 22 Children's Advil, 8, 19 Children's Motrin, 8, 19 chloral hydrate, 10 chlorambucil, 7 chloramphenicol, 6, 15, 16, 22 chlordiazepoxide, 11 chlordiazepoxide/ amitriptyline, 10 chlordiazepoxide/ clidinium, 18 chlorhexidine, 16 Chloromycetin, 6, 15 Chloromycetin Otic, 16 Chloroptic S.O.P., 22 chloroquine, 7 chloroquine/primaquine, 7 chlorothiazide, 7, 21 chlorphenesin, 20 chlorpheniramine/ phenylephrine/ hydrocodone, 24 chlorpheniramine/phenylpropanolamine/ methscopolamine, 24 chlorpheniramine/ phenyltoloxamine/ phenylephrine/phenylpropanolamine, 24 chlorpromazine, 10 chlorpropamide, 17 chlortetracycline, 22 chlorthalidone, 12 chlorzoxazone, 10, 20 Choledyl, 24 cholestyramine, 13 choline magnesium salicylate, 8, 20 Cholinergic Stimulants, 25 Cholinesterase Inhibitor Miotics, 21 Choloxin, 13
Decision and Order 127 F.T.C.
APPENDIX A
chorionic gonadotropin (inj), 17, 21 chymotrypsin, 23 ciclopirox, 15 Ciloxan, 22 cimetidine, 18 Cipro, 5 ciprofloxacin, 5, 22 cisapride, 19 citrate salts, 26 citric acid/ d-gluconic acid, 25 clarithromycin, 5 Claritin, 23 Claritin D, 24 Claritin Reditabs, 23 clemastine 2.68, 23 clemastine syrup, 23 Cleocin HCl, 6 Cleocin T, 15 Cleocin Vag, 21 clidinium, 18 Climara, 21 clindamycin, 6, 21 clindamycin topical, 15 Clinoril, 8, 19 clioquinol, 15 Clistin, 23 clobetasol .05% cream, lotion, ointment, 13 clocortolone pivalate 0.1% cream, 14 Cloderm, 14 clofazimine, 7 Clomid, 17, 21 clamiphene, 17, 21 clomipramine, 10 clonazepam, 9 clonidine, 12 clonidine transdermal, 12 clonidine/ chlorthalidone, 13 clorazepate, 11 cloroxine, 16 clotrimazole, 6, 15, 21 clotrimazole/ betamethasone, 15 clozapine, 10 Clozaril, 10 Coagulation Therapy, 11, 26 Codamine, 24 codeine, 8, 24 Codeine, 8 Codeine Phosphate Soln, 24 codeine/guaifenesin, 24 codeine/phenylephrine/ promethazine, 24 Cogentin, 9 Cognex, 9 Col Benemid, 20 colchicine, 20 Colestid, 13 colestipol, 13 collagenase, 16 Collagenase Santyl, 16 Colyte, 19
Combination Anticholinergics, 18 Combination Narcotic/ Analgesics, 8 Combiprex, 13 Combivent, 25 Compazine, 9, 19 Condylox, 16 conj estrogen vaginal cream, 21 conjugated estrogens, 21 conjugated estrogens/ medroxyprogesterone, 21 Constulose, 19 Copaxone, 9 Cordarone, 11 Cordran, 14 Cordran SP, 14 Cordran Tape Patch, 14 Coreg, 12 Corgard, 12 Cortef, 17, 20, 23 Cortenema, 19 Corticosteroids, 20, 23 corticotropin, 17 Cortifoam, 19 Cortisporin, 16, 23 Cortizide, 13 Cough & Cold Therapy, 23 Coumadin, 11, 26 Covera-HS, 12 Cozaar, 13 Creon, 19 Crinone, 21 Crixivan, 6 Crolom, 23 cromolyn, 23 cromolyn for inhalation, 25 cromolyn nasal, 16 cromolyn oral, 19 crotamiton, 16 Cuprimine, 20, 26 Cutivate, 14 cyanocobalamin, 26 Cyanocobalamin, 25 cyclobenzaprine, 10, 20 Cyclocort, 13 Cyclogyl, 22 cyclopentolate, 22 cyclophosphamide, 7 Cycloplegic Mydriatics, 22 cycloserine, 7 cyclosporine, 7 cyclosporine microemulsion, 7 Cylert, 10 cyproheptadine, 23 cytarabine, 7 Cytomel, 17 Cytosar-U, 7 Cytospaz, 25 Cytotec, 18 Cytovene, 6 Cytoxan, 7 Cytadren, 17
D Dalmane, 10 danazol, 17 Danocrine, 17 Dantrium, 10, 20 dantrolene, 10, 20 dapsone, 6 Dapsone, 6 Daranide, 22 Daraprim, 7 Darvocet N-100, 8 Darvon, 8 Darvon Cpd-65, 8 Daypro, 8, 19 DDAVP, 17 DDAVP Soln/Spray, 17 ddC, 6 ddI, 6 Debrisan, 16 Deca-Durabolin, 17 Decadron, 17, 20, 22, 23 Decaspray, 14 Declomycin, 5 Deconamine CX, 24 Deconamine SR, 24 Decongestant/ Antihistamines, 24 deferoxamine, 26 delavirdine, 6 Delhistine DM, 24 Deltaslin, 25 Deltasone, 17, 20, 23 Demadex, 12 demecarium, 22 demeclocycline, 5 Demerol, 8 Demser, 12 Demulen, 20 Denavir, 15 Depakene, 9 Depakote, 9 Depenit, 11 Depo-Provera, 7, 21 Deprol, 10 Dermacort, 14 Dermatologicals/ Topical Therapy, 13 Dermatop Emollient, 14 deserpidine/HCTZ, 12 deserpidine/ methyclothiazide, 12 Desferal, 26 desiccated thyroid, 17 desipramine, 10 desmopressin soln/ spray, 17 desmopressin tabs, 17 Desogen, 20 desogestrel/ ethinyl estradiol, 20 desonide 0.05% cream, ointment, lotion, 14 Desonide cream, 14 DesOwen, 14 desoximetasone 0.05% cream, 14 desoximethasone 0.05% gel, 13
desoximethasone 0.25% cream, ointment, 13 Desoxyn, 10 Desquam-X, 15 Desyrel, 10 Dexacidin, 23 Dexacort Resphaler, 25 Dexacort Turbinaire, 16, 25 dexamethasone, 16, 17, 20, 22, 23, 25 dexamethasone 0.04 % aerosol, 14 dexchlorpheniramine, 23 Dexedrine, 10 dextranomer, 16 dextromethorphan/ guaifenesin, 24 dextrothyroxine, 13 DHC Plus, 8 D.H.E.45, 9 DHT, 17 DiaBeta, 17 Diabetes Therapy, 17 Diabinese, 17 Diagnostics & Miscellaneous, 26 Diamox, 22 Diapid, 17 Diastat, 9 diazepam, 10, 11, 20 diazepam gel, 9 Dibenzyline, 12 dichlorphenamide, 22 diclofenac, 8, 19, 22 diclofenac potassium, 8, 19 dicloxacillin, 5 dicumarol, 11, 26 Dicumarol, 11, 26 dicyclomine, 18, 25 didanosine (ddI), 6 Didrex, 10 Didronel, 17 dienestrol cream, 21 diethylcarbamazine, 6 diethylpropion, 10 Differin, 15 diflorasone .05% cream, 13 diflorasone .05% ointment, 13 Diflucan, 6, 21 diflunisal, 8, 20 Digestive Enzymes, 19 digoxin, 11 dihydroergotamine (inj), 9 dihydrotachysterol, 17, 26 dihydroxyacetone, 16 Dilacor XR, 12 Dilantin, 9 Dilatrate-SR, 11 Dilaudid, 8 diltiazem, 12 diltiazem CD, 12 diltiazem SR, 12 dimercaprol, 26 Diovan, 13
MERCK & CO., INC., ET AL.
Decision and Order APPENDIX A
Dipentum, 19 diphenhydramine, 9, 23 diphenoxylate/atropine, 18 dipivefrin, 22, 23 Diprolene, 13, 14 Diprolene AF, 13 Diprosone, 13, 14 Diprosone Aerosol, 14 dipyridamole, 11, 26 Direct Acting Miotics, 22 dirithromycin, 5 disopyramide, 11 disopyramide CR, 11 disulfiram, 26 Ditropan, 10, 20, 25 Diupres, 13 divalproex sodium, 9 Dolobid, 8, 20 Dolophine, 8 Domeboro Otic, 16 donepezil, 9 Donnatal, 18 Dopar, 9 Doral, 10 dornase alpha, 25 dorzolamide, 22 Dostinex, 17 Dovonex, 16 doxazosin, 12, 25 doxepin, 10, 14, 16 doxycycline, 5 Dritho-scalp, 16 Drithocreme, 16 dronabinol, 9 Drugs to Treat Infertility/ IVF Agents, 21 Drysol, 16 Duaducin, 24 Duo-Medihaler, 25 Duragesic, 8 Duralutin, 21 Duraruss, 24 Duricef, 5 Dyazide, 12 Dyclone, 14 dyclonine, 14 Dymelor, 17 Dynabac, 5 Dynacin, 5 DynaCirc, 12 DynaCirc CR, 12 Dynapen, 5 Dyrceium, 12
E Ear, Nose & Throat Medications, 16 echothiophate, 21, 22 econazole, 15 Edecrin, 12 Edex, 25 EES, 5 EES w/sulf, 5 effervescent potassium, 26 Effexor, 10 Efudex, 16 Elase, 16 Elavil, 10
Eldepryl, 9 Eldopaque Forte, 16 Eldoquin Forte, 16 electrolyte solution, 19 Electrolytes, 26 Elimite, 16 Elixophyllin, 24 Elmiron, 25 Elocon, 14 Elocon ointment, 13 Emcyt, 7 Emgel, 15 EMLA, 14 Empirin/codeine, 8 E-Mycin, 5 enalapril, 12 enalapril/diltiazem, 13 enalapril/felodipine extended release, 13 enalapril/HCTZ, 13 Endep, 10 Endocrine/Diabetes, 17 Enduron, 12 Enduronyl, 12 enoxacin, 5 enoxaparin (inj), 11 Entex, 24 Entex LA, 24 Enulose, 19 enzymes, 26 ephedrine, 24 Ephedrine, 24 Epifrin, 23 epinephrine, 22, 24 Epinephrine, 23 epinephrine (inj), 23 epinephrine borate, 23 epinephrine HCl, 23 Epinephrine Mist, 24 epinephrine/ pilocarpine, 22 EpiPen, 23 EpiPen Jr., 23 Epivir, 6 Epogen, 7, 19 Eppy/N, 23 Equanil, 10 Ergamisol, 7 ergocalciferol, 25 ergoloid mesylates, 9 Ergomar, 9 Ergostat, 9 ergotamine, 9 ergotamine/caffeine, 9 ERYC, 5 Erycette, 15 EryDerm, 15 Erygel, 15 EryPED, 5 Ery-Tab, 5 Erythrocin, 5 Erythroid Stimulants, 19 erythromycin, 22 erythromycin base, delayed release, 5 erythromycin base, film & enteric coated tabs, 5 erythromycin estolate, 5
erythromycin ethylsuccinate, 5 erythromycin gel, 15 erythromycin pledgettes, 15 erythromycin polymer coated, 5 erythromycin stearate, 5 erythromycin T soln, 15 Erythromycins & Other Macrolides, 5 erythropoietin (inj), 7, 19 Esgic, 8, 9 Esidrix, 12 Eskalith, 10 estazolam, 10 esterified estrogens, 21 esterified estrogens/ methyltestosterone, 21 Estinyl, 21 Estrace, 21 Estraderm, 21 estradiol, 21 estradiol transdermal, 21 estradiol vaginal ring, 21 estramustine, 7 Estrabab, 21 Estratest, 21 Estring, 21 Estrogen Combinations, 21 Estrogens, 7, 21 Estrogens & Progestins, 21 estropipate, 21 Estrostep FE, 20 Estrovis, 21 ethacrynic acid, 12 ethambutol, 7 ethinyl estradiol, 21 ethinyl estradiol, norethindrone, 20 ethinyl estradiol/ ethynodiol, 20 ethinyl estradiol/ norethindrone, 20 ethionamide, 7 Ethmozine, 11 ethosuximide, 9 ethotoin, 9 etidronate, 17 etodolac, 8, 19 etoposide, 7 Eulexin, 7 Eurax, 16 Exactech, 18 Exactech Meter, 18 Exgest LA, 24 Exna, 12 Expectorant Combinations, 24 Extendryl SR, 24 Eye-Sed, 22
F famciclovir, 6 famotidine, 18 Famvir, 6 Fansidar, 7
Fasin, 10 felbamate, 9 Felbatol, 9 Feldene, 8, 19 felodipine, 12 Femara, 7 FemPatch, 21 Femstat, 21 fenoprofen, 8, 19 fentanyl lozenges, 8 Fentanyl Oralet, 8 fentanyl transdermal, 8 Feostat, 25 Fer-in-Sol, 25 ferrous fumarate, 25 ferrous gluconate, 25 ferrous sulfate, 25 Fertinex, 17, 21 fexofenadine, 23 fibrinolysin, 16 filgrastim (G-CSF) (inj), 7 filgrastim (inj), 19 finasteride, 17, 25 Fioricet, 8, 9 Fiorigen PF, 8, 9 Fiorinal, 8, 9 Fiorinal w/Codeine, 8 Flagyl, 6 flavoxate, 25 flecainide, 11 Flexeril, 10, 20 Flomax, 12 Flonase, 16, 25 Florinef, 17 Florone, 13 Flovent, 25 Floxin, 5 floxuridine, 7 flucinonide, 17 Flucinonide, 17 fluconazole, 6 fluconazole oral, 21 flucytosine, 6 Fludara, 7 fludarabine, 7 fludrocortisone, 17 Flumadine, 6 flunisolide, 16, 25 fluocinolone acetonide 0.01% cream, soln, 14 fluocinolone acetonide 0.025% cream, 14 fluocinolone acetonide 0.025% ointment, 14 fluocinonide .05% gel, ointment soln, 13 fluocinonide 0.05% cream, 14 fluorides, 25 fluorometholone, 22 Fluoroplex, 16 fluorouracil, 7, 16 fluoxetine, 10 fluoxymesterone, 7, 17 fluphenazine, 10 flurandrenolide .05% lotion, ointment, 14
Decision and Order 127 F.T.C.
APPENDIX A
flurandrenolide 0.05% cream, 14 flurandrenolide tape, 14 flurazepam, 10 flurbiprofen, 8, 19, 22 flutamide, 7 fluticasone, 16, 25 fluticasone propionate 0.005% ointment, 14 fluticasone propionate 0.05% cream, 14 fluvastatin, 13 fluvoxamine, 10 FML, 22 FML Forte, 22 FML SOP, 22 folic acid, 25 folinic acid, 7 Folvite, 25 Fosamax, 20 fosinopril, 12 FUDR, 7 Fulvicin P/G, 6 Fulvicin U/F, 6 Fungizone, 6, 15 Furacin, 16 Furadantin, 6 furazolidone, 6 furosemide, 12 Furoxone, 6
G gabapentin, 9 gamma 1b (inj), 19 ganciclovir, 6 Gantanol, 5 Gantrisin, 5, 22 Garamycin, 15, 22 Gastrocom, 19 Gastroenterology, 18 Gastrosed, 18 G-CSF, 7 gemfibrozil, 13 Genora 1/35, 20 Genotropin, 19 Gentacidin, 22 gentamicin, 22 gentamicin cream, oint, 15 Gen-Xene, 11 Geocillin, 5 Gesterol 50, 21 glatiramer (inj), 9 glimepiride, 17 glipizide, 17 glipizide ER, 17 Glucagon (inj), 17 Glucagon Emergency Kit, 17 Glucagon for Inj, 17 Glucofilm, 18 Glucometer ELI, 18 Glucometer ENC, 18 Glucometer II, 18 Glucophage, 17 Glucoscan, 18 Glucose Elevating Agents, 17 Glucostix, 18
Glucotrol, 17 Glucotrol XL, 17 glyburide, 17 glycopyrrolate, 18 Glynase, 17 GM-CSF, 7 GoLYTELY, 19 Gonadotropin & Related Agents, 17 Gout Therapy, 20 granisetron, 9, 19 Graqulex, 15 Grifulvin V, 6 Grisactin, 6 Grisactin Ultra, 6 griseofulvin, 6 Gris-PEG, 6 Growth Hormones, 19 Guaifed, 24 guaifenesin, 24 guaifenesin/phenylpropanolamine, 24 Guaifenex DM, 24 guanabenz, 12 guanadrel, 12 guanethidine, 12 guanfacine, 12 Gyrocaps, 24
H H2 Antagonists, 18 halcinonide .025% cream, 13 halcinonide 0.1% cream, soln, 13 halcinonide 0.1% ointment, 14 Halcion, 10 Haldol, 10 Haldrone, 17, 20 halobetasol .05% cream, ointment, 13 Halog, 13, 14 haloperidol, 10 Halotestin, 7, 17 HCA in Orabase, 16 Headache Therapy, 9 Helidac, 18 Hemorrhoidal HC, 19 Hemostatics, 11, 26 Heparin, 11, 26 heparin (inj), 11, 26 Herplex, 23 Hetrazan, 6 hexachlorophene, 16 Hexalen, 7 Hiprex, 6 Histinex HC, 24 Histussin D, 24 Histussin HC, 24 HIV/AIDS Therapy, 6 HIVID, 6 HMS, 22 homatropine, 22 homatropine/ hydrocodone, 24 Hormones, 7 Humalog, 17
Humatin, 6 Humatrope, 19 Humegon, 17, 21 Humibid DM, 24 Humibid LA, 24 Humorsol, 23 Humulin, 17 hyaluronidase (inj), 26 Hycodan, 24 Hycomine, 24 Hycomine Pediatric, 24 Hydergine LC, 9 hydralazine, 12 hydralazine/HCTZ, 13 hydralazine/reserpine/ HCTZ, 13 Hydrex, 7 hydrochlorothiazide, 12 hydrocodone, 8 hydrocodone/apap, 8 hydrocodone/ chlorpheniramine, 24 hydrocodone/phenylpropanolamine, 24 hydrocodone/ pseudoephedrine/ guaifenesin, 24 hydrocortisone, 16, 17, 20, hydrocortisone 1%, 19 hydrocortisone 2.5% cream, ointment, 14 hydrocortisone 2.5% lotion, 14 hydrocortisone acetate, 19 hydrocortisone buteprate 0.1%, 14 hydrocortisone butyrate 0.1% cream, ointment, soln, 14 hydrocortisone enema, 19 hydrocortisone foam, 19 hydrocortisone suppos, cream, 14 hydrocortisone valerate 0.2% cream, 14 hydrocortisone valerate 0.2% ointment, 14 Hydrocortone, 17, 20, 23 HydroDIURIL, 12 Hydromet, 24 hydromorphone, 8 Hydropres, 13 hydroquinone, 16 hydroquinone/ sunscreen, 16 hydroxychloroquine sulfate, [illegible] pyrimethamine, 7 hydroxyprogesterone, 21 hydroxyurea, 7 hydroxyzine HCl, 23 hydroxyzine pamoate, 23 Hygroton, 12 Hylorel, 12 hyoscyamine, 25 hyoscyamine caps, 18 hyoscyamine oral, 18
hyoscyamine SL, 18 Hypnotic Agents, 10 Hystakerol, 17, 26 Hytinic, 25 Hytone, 14 Hyzrin, 12, 25 Hyzaar, 13
I ibuprofen, 8, 19 ibuprofen suspension, 8, 19 idoxuridine, 23 Ilosone, 5 Ilotycin, 22 Imdur, 11 imipramine, 10 imiquimod, 16 Imitrex, 9 Immunosuppressant Drugs, 7 Imuran, 7, 20 indapamide, 12 Inderal, 12 Inderal LA, 12 Inderide, 13 indinavir, 6 Indocin, 8, 19 Indocin SR, 8, 19 indomethacin, 8, 19 indomethacin SR, 8, 19 InFeD, 26 Inflamase, 22 Inflamase Forte, 22 INH, 7 INH/B6, 7 INH/rifampin, 7 INH/rifampin/PZA, 7 Inhaled Corticosteroids, 25 insulin (beef/pork) (inj), 17 insulin (human) (inj), 17 Insulin Lispro (inj), 17 Insulin Syringes, 18 Insulin Therapy, 17 Intal, 25 Interferons, 19 Intranasal Steroids, 16, 25 Intron A, 19 Invirace, 6 iodine, 16 Iodine, 16 iodochlorhydroxyquin, 15 iodoquinal, 16 iodoquinol, 6 Ionamin, 10 Iopidine, 23 ipratropium, 16, 25 ipratropium/albuterol, 25 iron dextran, 26 Irrigation Solutions, 26 Ismelin, 12 Ismo, 11 isotharine, 25 isometheptene/ dichloralphenazone/ apap, 9
MERCK & CO., INC., ET AL.
Decision and Order APPENDIX A isoniazid, 7 isoproterenol, 25 isoproterenol/ phenylephrine, 25 Isoprin, 12 Isoptin SR, 12 Isopto Atropine, 22 Isopto Carbachol, 22 Isopto Eserine, 22 Isopto Homatropine, 22 Isopto Hyoscine, 22 Isordil, 11 Isordil Tembids, 11 isosorbide dinitrate, 11 isosorbide dinitrate SR, 11 isosorbide mononitrate, 11 isotretinoin, 15 isoxsuprine, 21 isradipine, 12 isradipine controlled release, 12 Isuprel Mistometer, 25 itraconazole, 6 itraconazole soln, 6 ivermectin, 6 J Jenest, 20 K Kaodene w/Paregoric, 18 Kaon, 26 Kaon Cl-10, 26 Kayciel Elixir, 26 Kayexalate, 26 KCl 10 mEq, SR cap, 26 KCl 10 mEq, SR tab, 26 KCl 10%, liquid, 26 KCl 8 mEq, SR cap, 26 KCl 8 mEq, SR tab, 26 K-Dur, 26 Keflex, 5 Keftab, 5 Kemadrin, 9 Kenalog, 14 Kenalog in Orabase, 16 Keralyt, 15 Keratolytics, 15 Kerlone, 12 ketoconazole, 6 ketoconazole cream, 15 ketoconazole shampoo, 15 ketoprofen, 8, 19 ketoprofen SR, 8, 19 ketorolac, 8, 19, 22 ketorolac (inj), 8, 19 Klaron, 15 Klonopin, 9 K-Lor, 26 Klor-Con, 26 Klor-Con/EF, 26 K-Tab, 26 Kwell, 16 Kytril, 9, 19 L labetalol, 12 Lac-Hydrin, 16 Lacrisert, 23 lactic acid, 16 lactulose, 19 Lamictal, 9 Lamisil, 6, 15 lamivudine, 6 lamotrigine, 9 Lampreme, 7 Lancets, 18 Lancets BD Ult, 18 Lancets Monole, 18 Lanoxicaps, 11 Lanoxin, 11 lansoprazole, 18 Lariam, 7 Larodopa, 9 Lasix, 12 latanoprost, 22 Lescol, 13 letrozole, 7 Leucovorin Cal, 7 Leukeran, 7 leukine, 7, 19 leuprolide (inj), 7, 21 levamisole, 7 Levaquin, 5 Levbid, 18 Levlen, 20 Levo Dromoran, 8 levobunolol, 21 levocabastine, 23 levocarnitine, 26 levodopa, 9 levofloxacin, 5 levomethadyl, 8 levonorgestrel/ethinyl estradiol, 20 Levora, 20 levorphanol, 8 levothyroxine, 17 Levoxyne, 17 Levsin, 18, 25 Levsin ex, 18, 25 Lexxel, 13 Librax, 18 Librium, 11 Lidex, 13, 14 Lidex E, 14 lidocaine, 14, 26 lidocaine (top), 26 lidocaine viscous, 16 Lilly Iletin, 17 Limbitrol, 10 lindane, 16 Lioresal, 10, 20 liothyronine, 17 liotrix, 17 Lipid/Cholesterol Lowering Agents, 13 Lipitor, 13 Liquid Pred, 17, 20, 23 lisinopril, 12 lisinopril/HCTZ, 13 lithium carb (capsule), 10 lithium carb (tablet), 10 lithium citrate, 10 Lithonate, 10 Lithostat, 6 Lithotabs, 10 Livostin, 23 Local Anesthetics, 26 Locoid, 14 Lodine, 8, 19 lodoxamide, 23 Loestrin, 20 Logen, 18 lomefloxacin, 5 Lomotil, 18 lomustine, 7 Long Acting Nitrates, 11 Loniten, 12 Lo/Ovral, 20 Lopid, 13 Lopressor, 12 Lopressor HCT, 13 Loprox, 15 Lorabid, 5 loracarbef, 5 loratadine, 23 loratadine/ pseudoephedrine, 24 lorazepam, 11 Lortab, 8 losartan, 13 losartan/HCTZ, 13 Lotensin, 12 Lotensin HCT, 13 Lotrel, 13 Lotrisone, 15 lovastatin, 13 Lovenox, 11 loxapine, 10 Loxitane, 10 Loxitane C, 10 Lozol, 12 Ludiomil, 10 Lupron, 7, 21 Luride, 25 Luvox, 10 lypressin, 17 Lysodren, 7 M Macrobid, 6 Macrodantin, 6 mafenide, 16 magnesium salicylate, 8 Magnesium Sulfate, 9 magnesium sulfate (inj), 9 Mandelamine, 6 MAO Inhibitors, 10 Maolate, 20 maprotiline, 10 Margesic, 8 Marinol, 9 masaprocol, 16 Materna, 25 Matulane, 7 Mavik, 12 Maxair, 25 Maxaquin, 5 Maxidex, 22 Maxitrol, 23 Maxivate, 13, 14 Maxzide, 12 Mazanol, 10 mazindol, 10 Mebaral, 9, 11 mebendazole, 6 Meclan, 15 meclizine, 9, 19 meclocycline, 15 meclofenamate, 8, 19 Meclomen, 8, 19 Medisense 2, 18 Medivert, 9 Medrol, 17, 20, 23 medroxyprogesterone, 21 medroxyprogesterone (inj), 7 medroxyprogesterone acetate, 21 medrysone, 22 mefloquine, 7 Megace, 7 megestrol, 7 Mellaril, 10 Mellaril S, 10 melphalan, 7 Menest, 21 menotropin (inj), 17, 21 meperidine, 8 mephenytoin, 9 mephobarbital, 9, 11 Mephyton, 11, 26 meprobamate, 10, 11 meprobamate/ benctyzine, 10 Mepron, 6 Meprospan, 11 mercaptopurine, 7 mesalamine, 19 Mesantoin, 9 mesoridazine, 10 Mestinon, 10 Metaprel, 24 metaproterenol, 24 metaproterenol 5% soln for inhalation, 24 metaproterenol aerosol, 25 metaproterenol soln 0.4%, 0.6% for inhalation, 24 metaxalone, 10, 20 metformin, 17 methadone, 8 methamphetamine, 10 methazolamide, 22 methenamine hippurate, 6 methenamine mandelate, 6 methenamine/phenylsalicylate/atropine/ hyoscyamine/benzoic acid/methylene blue, 25 Methergine, 21 methimazole, 17 methocarbamol, 10, 20 methotrexate, 7, 20 Methotrexate, 7 methoxsalen, 16 methscopolamine, 18 methsuximide, 9 methylclothiazide, 12 methyldopa, 12 methyldopa/HCTZ, 13
Decision and Order 127 F.T.C.
APPENDIX A
methylergonovine, 21 methylphenidate, 10 methylprednisolone, 17.
20, 23 methyltestosterone, 17 Methyltestosterone, 17 methysergide, 9 Meticorten, 17 Metimyd, 23 metipranolol, 21 metoclopramide, 19 metolazone, 12 metoprolol, 12 metoprolol LA, 12 metoprolol/HCTZ, 13 Metrodin, 17, 21 MetroGel, 15 MetroGel-Vag, 21 metronidazole, 6, 15 metronidazole vaginal gel, 21 metyrosine, 12 Mevacor, 13 mexiletine, 11 MexitiI, 11 Miacalcin, 17, 20 mibefradil, 12 miconazole, 21 Micro-K 10 mEq, 26 Micro-K 8 mEq, 26 microcrystalline, 6 Micronase, 17 Micronor, 21 Midamor, 12 midodrine, 9, 26 Midrin, 9 Migraine & Cluster Headache Therapy, 9 Milonin, 9 Miltown, 10 Minipress, 12 Minitran, 11 Minizide, 13 Minocin, 5 minocycline, 5 minoxidil, 12 Mintezol, 6 Miochol, 22 Miostat, 22 Miradon, 11, 26 Mirapex, 9 mirtazapine, 10 Miscellaneous Psychotherapeutic Agents, 10 Miscellaneous Agents, 16, 26 Miscellaneous Analgesics, 8 Miscellaneous Anti-Infectives, 6 Miscellaneous Antidepressants, 10 Miscellaneous Antineoplastic Drugs, 7 Miscellaneous Antipsychotics, 10
Miscellaneous Antivirals, 6 Miscellaneous Coagulation Agents, 11, 26 Miscellaneous Dermatologicals, 16 Miscellaneous Gastrointestinal Agents, 19 Miscellaneous Hormones, 17 Miscellaneous Neurological Therapy, 9 Miscellaneous OB/GYN, 21 Miscellaneous Ophthalmologics, 23 Miscellaneous Otic Preparations, 16 Miscellaneous Pulmonary Agents, 25 Miscellaneous Rheumatological Agents, 20 Miscellaneous Urologicals, 25 Miscellaneous Vitamins, Hematinics & Electrolytes, 26 misoprostol, 18 mitotane, 7 Moban, 10 Mobidin, 8 Modicon, 20 Moduretic, 12 moexipril, 12 molindone, 10 mometasone furoate 0.1% cream, lotion, 14 mometasone furoate 0.1% ointment, 13 Monistat 3, 21 Monistat Dual Pak, 21 monobenzone, 16 Monodox, 5 Monoject Ass't, 18 Monoject Syr 2, 18 Monoket, 11 Monopril, 12 moricizine, 11 Morphine Sulfate, 8 morphine sulfate supp, 8 morphine sulfate, controlled release, 8 morphine sulfate, soluble tabs, 8 Motrin, 8, 19 MS Contin, 8 MS oral concentrate, 8 Mucomyst, 25 mupirocin, 15 Muscle Relaxants & Antispasmodic Therapy, 10, 20 Musculoskeletal & Rheumatology, 19 Muse, 25
MVI w/fl, 25 MVL prenatal, 25 Myambutol, 7 Myasthenia Gravis, 10 Mycelex, 15 Mycelex troche, 6 Mycelex-G, 21 Mycifradin tabs, 7 Mycobutin, 7 Mycolog II, 15 mycophenolate mofetil, 7 Mycostatin, 6, 15, 21 Mydriacyl, 22 Myeloid Stimulants, 19 Mykrox, 12 Myleran, 7 Myphetane DX, 23 Mysoline, 9 Mytelase, 10 Mytussin AC, 24
N nabumetone, 8, 19 nactamycin, 22 nadolol, 12 nadolol/ bendroflumethiazide, 13 nafarelin acetate, 17, 21 naftifine, 15 Naftin, 15 Naldelate, 24 Nalfon, 8, 19 nalidixic acid, 6 naloxone (inj), 8 naltrexone, 8 nandrolone decanoate, 17 naphazoline/antazoline, 22 Naprelan, 8, 19 Naprosyn, 8, 19 naproxen, 8, 19 naproxen sod, 8, 19 Narcan, 8 Narcotic Analgesics, 8 Narcotic Antagonists, 8 Narcotics, 8 Nardil, 10 Nasacort, 16, 25 Nasacort AQ, 16, 25 Nasalchrom, 16, 25 Nasalide, 16, 25 Nascobal, 26 Natacyn, 22 Naturetin-5, 12 Navane, 10 Nebupent, 6 nedocromil, 25 N.E.E., 20 Needles and Sy, 18 nefazodone, 10 NegGram, 6 nelfinavir, 6 Nelova, 20 Neo-Decadron, 23 neomycin, 6, 7 Neomycin, 6 neomycin/bacitracin/ polymyxin/HC, 23
neomycin/ dexamethasone, 23 neomycin/fluocinolone, 15 neomycin/polymyxin/ bacitracin ointment, 22 neomycin/polymyxin/ dexamethasone, 23 neomycin/polymyxin/ HC, 16— neomycin/polymyxin/ prednisolone, 23 Neoral, 7 Neosar, 7 Neosporin, 22 neostigmine (inj), 10 Neosynalar, 15 Neo-Synephrine, 22 Neptazane, 22 Neupogen, 7, 19 Neurontin, 9 nevirapine, 6 Niacin, 13, 25 Niazid B6, 7 nicardipine, 12 nicardipine SR, 12 Nicorette DS, 26 Nicorette gum, 26 nicotine nasal spray, 26 nicotine polacrilex, 26 nicotinic acid, 13, 25 Nicotrol NS, 26 nifedipine, 12 nifedipine XL, 12 Nilandron, 7 Nilstat, 6 nilutamide, 7 nimodipine, 12 Nimotop, 12 nisoldipine, 12 Nitrates, 11 Nitrobid, 11 Nitro-Bid, 11 Nitrodisc, 11 Nitro-Dur, 11 nitrofurantoin, 6 nitrofurantoin macrocrystals, 6 nitrofurantoin monohydrate macrocrystals, 6 nitrofurazone, 16 Nitrogard, 11 nitroglycerin, 11 nitroglycerin (oral), 11 nitroglycerin ointment, 11 nitroglycerin SL, 11 nitroglycerin spray, 11 Nitrol, 11 Nitrolingual Spray, 11 Nitrostat, 11 nizatidine, 18 Nizoral, 6, 15 Nolamine, 24 Nolvadex, 7 Non-Narcotic Analgesics, 8 Non-Steroidal Anti- Inflammatory Agents,
MERCK & CO., INC., ET AL.
Decision and Order APPENDIX A Nor QD, 21 Nordette, 20 norethindrone, 21 Norethindrone, 21 norethindrone acetate, 21 norethindrone/ethinyl estradiol, 20 norethindrone/ mestranol, 20 Norflex, 10, 20 norfloxacin, 5, 22 Norgesic, 10 norgestimate/ ethinyl estradiol, 20 norgestrel, 21 Norgestrel, 21 norgestrel/ ethinyl estradiol, 20 Norinyl, 20 Norlutate, 21 Norlutin, 21 Normodyne, 12 Noroxin, 5 Norpace, 11 Norpace CR, 11 Norpramin, 10 nortriptyline, 10 Norvasc, 12 Norvir, 6 Novacet, 15 Novafed, 24 NovoFine Ins N, 18 Novolin, 17 Novo-Nordisk, 17 NSAIDs, 8, 19 Nuco-Tuss Exp, 24 NuLYTELY, 19 Nutropin, 19 Nutropin AQ, 19 nystatin, 6 Nystatin, 21 nystatin topical, 15 nystatin vaginal, 21 nystatin/triamcinolone, 15 O Obstetric & Gynecology, 20 octreotide (inj), 7, 17 Ocufen, 22 Ocuflox, 22 Ocusert Pilo-20, 22 ofloxacin, 5, 22 Ogen, 21 olanzapine, 10 olopatadine, 23 olsalazine, 19 omeprazole, 18 Omnipen, 5 OMS, 8 ondansetron, 9, 19 One Touch, 18 One Touch II, 18 One Touch Prof, 18 Ophthalmology, 21 opium, 8 opium preparations, 18 Opium Tincture, 18 Optimine, 23 OptiPranolol, 21 Oral Contraceptives & Related Agents, 20 Oral Drugs for Glaucoma, 22 Oral Hypoglycemic Agents, 17 Orap, 10 Orasone, 17, 20, 23 Oretic, 12 Oreticyl, 12 Orinase, 17 ORLAAM, 8 orphenadrine, 10 orphenadrine/asa/ caffeine, 20 Ortho-Cept, 20 Ortho-Cyclen, 20 Ortho Dienestrol, 21 Ortho-Est, 21 Ortho-Novum, 20 Ortho-Novum 777, 20 Ortho-Novum 10/11, 20 Ortho Tri-Cyclen, 20 Orudis, 8, 19 Oruvail, 8, 19 Osteoporosis Therapy, 20 Other Antihypertensive Combinations, 13 Other Glaucoma Drugs, 22 Other Rheumatologics, 20 Other Ulcer Therapy, 18 Otic Steroid/Antibiotic, 16 Ovcon, 20 Ovral, 20 Ovrette, 21 Ovulatory Stimulants, 17 oxamniquine, 6 Oxandrin, 17 oxandrolone, 17 oxaprozin, 8, 19 oxazepam, 11 oxiconazole, 15 Oxistat, 15 Oxsoralen, 16 oxtriphylline, 24 oxybutynin, 10, 20, 25 oxycodone, 8 OxyContin, 8 Oxytotics, 21 oxytocin spray, 21 P P1E1, 22 P2E1, 22 P3E1, 22 P4E1, 22 P6E1, 22 Pamelor, 10 Pamine, 18 Pancrease, 19 Pancrease MT, 19 pancreatin, 19 pancrelipase, 19 Pandel, 14 papaverine, 12 Paradione, 9 Paraflex, 10, 20 Parafon Forte DSC, 10, 20 Paral, 11 paraldehyde, 11 paramethadione, 9 paramethasone, 17, 20 paregoric, 18 Paregoric USP, 18 Parlodel, 9 Parnate, 10 paromomycin sulfate, 6 paroxetine, 10 Passer, 7 Patanol, 23 Pavabid, 12 Paxil, 10 PBZ, 23 PBZ SR, 23 PCE, 5 Pediaflor Drops, 25 Pediazole, 5 Peganone, 9 pemoline, 10 Pen-Vee K, 5 penciclovir, 15 Penetrex, 5 penicillamine, 20, 26 penicillin G, 5 penicillin VK, 5 Penicillins, 5 Pentam, 6 pentamidine isethionate (inh), 6 Pentasa, 19 pentazocine, 8 pentazocine/apap, 8 pentazocine/naloxone, 8 pentosan polysulfate/ sodium, 25 pentoxifylline, 11, 26 Pepcid, 18 Percocet, 8 Percodan, 8 pergolide, 17 pergolide mesylate, 9 Pergonal, 17, 21 Periactin, 23 Peridex, 16 Permax, 9, 17 permethrin, 16 Permitil, 10 perphenazine, 10 perphenazine/ amitriptyline, 10 Persa-Gel, 15 Persa-Gel W, 15 Persantine, 11, 26 Pertofrane, 10 phenacemide, 9 Phenaphen, 8 Phenazine, 10 phenazopyridine, 6, 25 phendimetrazine, 10 phenelzine, 10 Phenergan, 9, 19, 23 Phenergan VC, 24 Phenergan/Co, 24 phenobarbital, 9 Phenothiazines, 10 phenoxybenzamine, 12 phensuximide, 9 phentermine, 10 phentolamine, 12 Phenurone, 9 phenylbutazone, 19 phenylephrine, 22 Phenylfenesin LA, 24 phenylpropanolamine/ chlorpheniramine/ apap, 24 phenylpropanolamine/ chlorpheniramine/ phenylephrine, 24 phenylpropanolamine/ guaifenesin/ phenylephrine, 24 phenylpropanolamine/ phenyltoloxamine/ pyrilamine/ pheniramine, 24 phenytoin, 9 Phospholine Iodide, 21, 22 Phrenilin, 8, 9 Phrenilin Forte, 8, 9 physostigmine, 22 phytonadione, 11, 26 Pilagan, 22 Pilocar, 22 pilocarpine, 22 pilocarpine gel, 22 pilocarpine, oral, 26 Pilopine HS, 22 pimozide, 10 pindolol, 12 piperazine, 6 Piperazine, 6 pirbuterol, 25 piroxicam, 8, 19 Piressin, 17 Plaquenil, 7 Plendil, 12 podofilox, 16 Podofin, 16 podophyllum, 16 Polaramine, 23 Poly-Histine CS, 24 Polycillin, 5 Polycitra-K, 26 Poly-Histine-D, 24 Poly-Histine DM, 24 Poly-Histine-D Ped, 24 Polymox, 5 polymyxin B, 22 Polymyxin B, 22 polymyxin B/ trimethoprim, 22 Poly-Pred, 23 polysaccharide iron complex, 25 polythiazide, 12 Polytrim, 22 Poly-Vi-Flor, 25 Pontocaine, 23 Posicor, 12 potassium citrate, 6, 26
Decision and Order 127 F.T.C.
APPENDIX A
potassium gluconate liquid, 26 potassium iodide, 24 powdered potassium, 26 pramipexole, 9 pramoxine/HC, 19 Pravachol, 13 pravastatin, 13 praziquantel, 6 prazosin, 12 prazosin/polythiazide, 13 Precision Meter, 18 Precision QID, 18 Precose, 17 Pred-Forte, 22 Pred-Mild, 22 prednicarbate, 14 prednisolone, 22 prednisolone sodium phosphate, 22 prednisolone syrup, 17, 20, 23 prednisone, 20, 23 prednisone liquid, 17, 20, 23 prednisone tablet, 17 Prelone, 17, 20, 23 Premarin, 21 Premphase, 21 Prempro, 21 Prenate Ultra, 25 Prestige Test, 18 Prevacid, 18 prilocaine/lidocaine, 14 Prilosec, 18 primaquine, 7 Primaquine, 7 primidone, 9 Prinivil, 12 Prinzide, 13 Pro-Banthine, 18, 25 ProAmatine, 9, 26 probenecid, 20 probenecid w/colchicine, 20 procainamide, 11 procainamide SR, 11 procaine (inj), 5 Procan SR, 11 Procanbid, 11 procarbazine, 7 Procardia, 12 Procardia XL, 12 prochlorperazine, 9, 19 prochlorperazine (supp), 9, 19 Procrit, 7, 19 Proctocort, 19 ProctoFoam-HC, 19 procyclidine, 9 Profasi HP, 17, 21 Profenal, 22 progesterone gel, 21 progesterone inj., 21 Progesterone supp. 21 progesterone vaginal suppos, 21 Progestin Only, 21
Progestins, 21 Prograf, 7 Prolastin, 26 Prolixin, 10 Proloprim, 6 promazine, 9 promethazine, 9, 19, 23 promethazine (supp), 9, 19 Promethazine VC/Cod, 24 promethazine/codeine, 24 promethazine/ phenylephrine, 24 Pronestyl, 11 Pronestyl SR, 11 propafenone, 11 propantheline, 18, 25 proparacaine, 23 Propine, 22, 23 Propoxyphene, 8 Propoxyphene Compound, 8 propoxyphene HCl/apap, 8 propoxyphene napsylate/ apap, 8 propoxyphene/asa/ caffeine, 8 propranolol, 12 propranolol LA, 12 propranolol/HCTZ, 13 Propulsid, 19 propylthiouracil, 17 Propylthiouracil, 17 Proscar, 17, 25 ProSom, 10 Prostaglandins, 18 Prostigmin, 10 Proton Pump Inhibitors, 18 Protostat, 6 protriptyline, 10 Protopin, 19 Proventil, 24, 25 Proventil Repetabs, 24 Provera, 21 Prozac, 10 pseudoephedrine, 24 pseudoephedrine/carbinoxamine, 24 pseudoephedrine/ carbinoxamine/ dextromethorphan, 24 pseudoephedrine/ chlorpheniramine, 24 pseudoephedrine/codeine/ guaifenesin, 24 pseudoephedrine/ giaofenesom/ guaifenesin, 24 pseudoephedrine/ guaifenesin, 24 pseudoephedrine/ guaifenesin SR, 24 pseudoephedrine/ hydrocodone, 24 Psorcon, 13 Psychotherapeutic Drugs, 10 Pulmicort, 25 Pulmonary Agents, 24
Pulmozyme, 25 Purinethol, 7 pyrantel, 6 pyrazinamide, 7 Pyrazinamide, 7 Pyridium, 6, 25 pyridostigmine (inj), 10 pyrimethamine, 7
Q Quarzan, 18 quazepam, 10 Questran, 13 Questran Light, 13 Quibron T, 24 quinacrine, 7 Quinaglute, 11 Quinbron T, 24 quinesurol, 21 Quinidex, 11 quinidine 200 sulfate, 11 quinidine 300 sulfate, 11 quinidine ER, 11 quinidine gluconate, 11 quinidine polygalacturonate, 11 Quinidine Sulfate, 11 quinine sulfate, 7 Quinnam, 7 Quinolones, 5 Quinora, 11
R ramipril, 12 ranitidine, 18 ranitidine bismuth citrate, 18 Rapid Acting Nitrates, 11 Regitine, 12 Reglan, 19 Relafen, 8, 19 Remeron, 10 Renacidin, 25 Renese, 12 Renoquid, 5 Rescriptor, 6 reserpine, 12 reserpine/ chlorothiazide, 13 reserpine/HCTZ, 13 reserpine/ hydroflumethiazide, 13 Respiratory, Allergy, Cough & Cold, 23 Restoril, 10 Retin A, 15 Retin A micro, 15 Retrovir, 6 ReVia, 8 Rezulin, 17 Rheumatrex, 7, 20 Rhinocort, 16, 25 Ridaura, 20 rifabutin, 7 Rifadin, 7 Rifamate, 7 rifampin, 7 Rifater, 7
Rilutek, 9 riluzole, 9 rimantadine, 6 rimexolone, 22 Risperdal, 10 risperidone, 10 Ritalin, 10 ritonavir, 6 RMS Supp, 8 Robaxin, 10, 20 Robinul, 18 Robitussin AC, 24 Robitussin DAC, 24 Rocaltrol, 17, 26 Roferon A, 19 Rondec, 24 Rondec DM, 24 Rowsa, 19 Roxicet, 8 Roxicodone, 8 Rufen, 8, 19 Rythmol, 11
S Salagen, 26 Saleto-D, 8, 20 Salflex, 8, 20 salicylamide, 8, 20 salicylate salts, 8, 20 Salicylates, 8, 20 salicylic acid gel, 15 salmeterol, 25 salsalate, 8, 20 Salutensin, 13 Sandimmune, 7 Sandostatin, 7, 17 Sansert, 9 saquinavir, 6 sargramostim (GM-CSF) (inj), 7 sargramostim (inj), 19 scopolamine, 9, 19, 22 Sebaguin, 16 Sebizon, 16 Sectral, 12 Selective Serotonin Reuptake Inhibitors, 10 selegiline, 9 selenium sulfide 2.5%, 1%, 16 Selsun Rx, 16 Semprex D, 24 Septisol Foam, 16 Septra, 5 Septra DS, 5 SER-AP-ES, 13 Serax, 11 Serenil, 10 Serevent, 25 Seromycin, 7 Serophene, 17, 21 Serpasil, 12 sertraline, 10 Serzone, 10 Silvadene, 15 silver nitrate, 23 Silver Nitrate, 23 silver sulfadiazine, 15
MERCK & CO., INC., ET AL.
Decision and Order APPENDIX A Simron, 25 simvastatin, 13 Sinemet, 9 Sinemet CR, 9 Sinequan, 10 Skelaxin, 10, 20 Skelid, 17 Slo-bid Gyrocaps, 24 Slo-Phyllin, 24 Slow K, 26 Smoking Deterrents, 26 sod fluoride, 25 sodium polystyrene sulfonate, 26 sodium salicylate, 8 Sodium Salicylate, 8 sodium sulfacetamide, 22 sodium sulfacetamide lotion, 15 sodium thiosulfate, 15 Soft Touch, 18 Solaquin Forte, 16 Solatene, 25 Solfoton, 9 Solganal, 20 Soma, 10, 20 Soma Comp/Codeine, 10 somatropin (inj), 19 sotalol, 11 Sparine, 9 Specialized OB/GYN Drugs, 21 Spectazole, 15 spironolactone, 12 spironolactone/HCTZ, 12 Sporanox, 6 SSD, 15 SSKI, 24 Stadol, 8 Stadol NS, 8 stavudine, 6 Stelazine, 10 Steroid-Antibiotic Combinations, 23 Steroid-Sulfonamide Combinations, 23 Steroids, 22 Stromectol, 6 succimer, 26 sucralfate, 18 Sulamyd, 22 Sular, 12 Sulfacet R, 15 sulfacetamide lotion, 16 sulfacetamide/ phenylephrine, 22 sulfacetamide/ prednisolone, 23 sulfacetamide/sulfur, 15 sulfacytine, 5 sulfadiazine, 5 Sulfadiazine, 5 sulfamethoxazole, 5 sulfamethoxazole/ trimethoprim, 5 Sulfamylon, 16 sulfanilamide, 5 Sulfanilamide, 5 sulfanilamide vaginal, 21 sulfapyridine, 16 Sulfapyridine, 16 Sulfas & Related Agents, 5 sulfasalazine, 5, 19, 20 sulfisoxazole, 5, 22 sulfisoxazole/ erythromycin, 5 Sulfonamides, 22 Sulfoxyl Strong, 15 sulindac, 8, 19 Sultrin, 21 sumatriptan (inj), 9 sumatriptan (nasal), 9 sumatriptan (tabs), 9 Sumycin, 5 Suprax, 5 suprofen, 22 Sure-Dose 28G1, 18 Sure-Dose 29G1, 18 Surestep, 18 sutilains, 16 Symadine, 6 Symmetrel, 6, 9 Sympathomimetics, 23 Syn Rx, 24 Synalar, 14 Synalgos-DC, 8 Synarel, 17, 21 Synthroid, 17 Syntocinon, 21 T Tace, 7, 21 tacrine, 9 tacrolimus, 7 Tagamet, 18 Talacen, 8 Talwin, 8 Talwin Nx, 8 Tambocor, 11 tamoxifen, 7 tamsulosin, 12 Tapazole, 17 Tarka, 13 Tavist 2,68, 23 Tavist suspension, 23 tazarotene gel, 16 Tazorac, 16 T-Cort, 17 Teczem, 13 Tegretol, 9 temazepam, 10 Temovate, 13 Tenex, 12 Tenormin, 12 Tenute, 10 Terazol, 21 terazosin, 12, 25 terbinafine cream, 15 terbinafine oral, 6 terbutaline, 21, 24 terconazole, 21 Terumo Ins Syr, 18 Testlac, 7 Tessalon Perle, 24 Testex, 17 Testoderm, 17 testolactone, 7 Testopel, 17 testosterone, 17 testosterone propionate (inj), 17 testosterone transdermal, 17 Testred, 17 tetracaine, 23 tetracycline, 5, 15 Tetracyclines, 5 Theo-Dur, 24 Theochron, 24 Theoclear, 24 Theolair, 24 Theolair SR, 24 theophylline anhydrous, 24 theophylline immediate release, 24 theophylline timed release, 24 Therapy for Acne, 15 thiabendazole, 6 Thiazide & Related Diuretics, 12 thiethylperazine, 9 thioguanine, 7 Thioguanine, 6-TG, 7 thiondazine, 10 thiothixene, 10 Thorazine, 10 Thyroid, 17 Thyroid Hormones, 17 Thyroid SPT, 17 Thyrolar, 17 Tiazac, 12 Ticlid, 11, 26 ticlopidine, 11, 26 Tigan, 9, 19 Tildae, 25 tiludronate, 17 Timolide, 13 timolol, 12 timolol hemihydrate, 21 timolol maleate, 21 timolol ophth, 21 timolol/HCTZ, 13 Timoptic, 21 Timoptic XE, 21 Tindal, 10 Tinver, 15 tioconazole, 21 tioconazole ointment, 21 TobraDex, 23 tobramycin, 22 tobramycin/ dexamethasone, 23 Tobrex, 22 tocainide, 11 Tofranil, 10 tolazamide, 17 tolbutamide, 17 Tolectin, 8, 19 Tolinase, 17 tolmetin, 8, 19 Tonocard, 11 Topamax, 9 Topical Anesthetics, 14 Topical Antibacterials, 15 Topical Antifungals, 15 Topical Antivirals, 15 Topical Corticosteroids, 13, 14 Topical Enzymes, 15 Topical Scabicides/ Pediculicides, 16 Topicort, 13 Topicort LP, 14 Topicylene, 15 topiramate, 9 Toposide, 7 Toprol XL, 12 Toradol, 8, 19 Torecan, 9 Tornalate, 25 torsemide, 12 Totacillin, 5 T-Phyl, 24 Tracer BG, 18 tramadol, 8 Trandate, 12 trandolapril, 12 trandolapril/verapamil extended release, 13 Transderm-Nitro, 11 Transderm-Scop, 9, 19 transdermal nitroglycerin patch, 11 Tranxene, 11 tranylcypromine, 10 Travase, 16 trazodone, 10 Trector-SC, 7 Trental, 11, 26 tretinoin, 15 Trexan, 8 Triad, 8, 9 triamcinolone, 16, 17, 20, 23, 25 triamcinolone acetonide, 16, 25 triamcinolone acetonide 0.025% cream, ointment, 14 triamcinolone acetonide 0.025% lotion, 14 triamcinolone acetonide 0.1% cream, 14 triamcinolone acetonide 0.1% lotion, 14 triamcinolone acetonide 0.1% ointment, 14 triamcinolone acetonide 0.5% cream, ointment, 14 triamcinolone in orabase, 16 triamcinolone spray, 14 triamterene, 12 triamterene/HCTZ, 12 Triavil, 10 Triaz, 15 triazolam, 10 Tricyclics, 10 Tridione, 9
Decision and Order 127 F.T.C.
APPENDIX A
triethanolamine oleate, 16 trifluoperazine, 10 trifluridine, 23 trihexyphenidyl, 9 Trilafon, 10 Tri-Levlen, 20 Trilisate, 8, 20 trimethadione, 9 trimethobenzamide, 9, 19 trimethobenzamide (inj), 9, 19 trimethobenzamide (supp), 9, 19 trimethoprim, 6 Trimox, 5 Trinalin, 24 Tri-Norinyl, 20 trioxsalen, 16 tripelennamine, 23 Triphasil, 20 triple sulfa, 21 Triple Sulfa No. 2, 5 Trisoralen, 16 trisulfapyrimidine, 5 Tritec, 18 Tri-Vi-Flor, 25 troglitazone, 17 tropicamide, 22 Trusopt, 22 trypsia, 15 Trysol, 21 T-STAT, 15 Tuinal, 11 Tussionex, 24 Tylenol/codeine, 8 Tylox, 8
U Ulcer Therapy, 18 Ultracef, 5 Ultram, 8 ultramicrocrystalline, 6 Ultrase, 19 Ultrase MT, 19 Ultravate, 13 Uniphyl, 24 Unipres, 13 Univasc, 12 uracil mustard, 7 Uracil Mustard, 7 Urecholine, 25 Urex, 6 Urinary Anesthetics, 25 Urinary Tract Agents, 6 Urised, 25 Urispas, 25 Urocit-K, 6, 26 urofollitropin (inj), 17, 21 Urologicals, 25 ursodiol, 19 Uticort, 14
V Vaginal Antifungals, 21 Vaginal Cleanser/ Anti-Infectives, 21 Vagistat, 21 Vagistat-1, 21
valacyclovir, 6 Valisone, 14 Valium, 10, 11, 20 valproic acid, 9 valsartan, 13 Valtrex, 6 Vancenase, 25 Vancenase AQ, 16, 25 Vancenase AQ DS, 25 Vancenase DS, 16 Vancenase pockethaler, 16 Vanceril, 25 Vanceril DS, 25 Vancocin, 6 Vancomycin, 6 Vansil, 6 Vantin, 5 Vascor, 12 Vaseretic, 13 Vasocidin, 23 Vasoconstrictor Decongestants, 22 Vasodilan, 21 Vasodilators, 12 vasopressin (inj), 17 Vasotuff, 22 Vasotec, 12 Velosef, 5 venlafaxine, 10 Ventolin, 24, 25 Ventolin Rotacaps, 25 VePesid, 7 verapamil, 12 verapamil SR, 12 verapamil, long acting, 12 Verelan, 12 Vermox, 6 Vertin, 9 Vesanoid, 7 Vexol, 22 Vibramycin, 5 Vicodin, 8 vidarabine, 23 Videx, 6 Vira-A, 23 Vitacept, 6 Viramune, 6 Viroptic, 23 Viscous Xylocaine, 16 Visken, 12 Vistaril, 23 Vitadyne, 16 vitamin A, 25 vitamin B12, 25 Vitamin K, 11, 26 Vitamins & Hematinics, 25 Vitamins A, D, C with fluoride, 25 Vitamins, Hematinics & Electrolytes, 25 Vivactil, 10 Vivelle, 21 Volmax ER, 24 Voltaren, 8, 19, 22 VOSol, 16 VOSol HC, 16
W warfarin, 11, 26 Wellbutrin, 10 Westcort, 14 Wycillin, 5 Wydase, 26 Wygesic, 8 Wytensin, 12
X Xalatan, 22 Xanax, 11 Xanthines, 24 Xylocaine spray, 14 Xylocaine, Viscous, 14
Y Yodoxin, 6
Z zafirlukast, 25 zalcitabine (ddC), 6 Zantac, 18 Zarontin, 9 Zaroxolyn, 12 Zebeta, 12 Zerit, 6 Zestoretic, 13 Zestril, 12 Ziac, 13 zidovudine (AZT), 6 zileuton, 25 zinc sulfate, 22 Zithromax, 5 Zocor, 13 Zofran, 9, 19 Zoloft, 10 zolpidem, 10 Zonalon, 14, 16 Zorprin, 8, 20 Zovirax, 6, 15 Zyban, 26 Zyflo, 25 Zyloprim, 20 Zyprexa, 10 Zyrtec, 23 Zyrtec Syrup, 12, 23
MERCK & CO., INC., ET AL. 207
156 Decision and Order
APPENDIX A
Merck-Medco Managed Care, L.L.C.
A subsidiary of Merck & Co., Inc.
Merck-Medco Managed Care, L.L.C.; PAID Prescriptions, L.L.C.; and Merck-Medco Rx Services pharmacies are subsidiaries of Merck & Co., Inc.
© 1998 Merck-Medco Managed Care, L.L.C.
Complaint 127 F.T.C.
IN THE MATTER OF
SUMMIT TECHNOLOGY, INC.
CONSENT ORDER, ETC., IN REGARD TO ALLEGED VIOLATION OF SEC. 5 OF THE FEDERAL TRADE COMMISSION ACT
Docket 9286. Complaint, March 24, 1998--Decision, Feb. 23, 1999
This consent order, among other things, prohibits the Massachusetts-based marketer of laser equipment for eye surgery from entering into, enforcing or maintaining any contract, agreement, joint venture or other combination with VISX, Inc., to fix, maintain or control any price or the terms or conditions associated with the purchase, license or use of any product, device or technology that uses a laser to perform any medical procedure, including ophthalmic surgery.
Participants
For the Commission: Michael McNeely, Veronica Kayne, Chul Pak, Dana Abrahamsen, Jeremy Cubert, Joshua Newberg, Jacqueline Berman, Beverly Dodson, David von Nirschl, Daniel Ducore, William Baer, Louis Silvia and Curtis Wagner.
For the respondent: Michael Sohn and Mark Merley, Arnold & Porter, Washington, D.C.
COMPLAINT
Pursuant to the provisions of the Federal Trade Commission Act, and by virtue of the authority vested in it by said Act, the Federal Trade Commission, having reason to believe that Summit Technology Inc. ("Summit"), a corporation, and VISX, Inc. ("VISX"), a corporation, hereinafter sometimes referred to as respondents, have violated the provisions of said Act, and it appearing to the Commission that a proceeding by it in respect thereof would be in the public interest, hereby issues its complaint, stating its charges as follows:
BACKGROUND
1. Respondent Summit is a corporation organized, existing, and doing business under and by virtue of the laws of Massachusetts with its office and principal place of business located at 21 Hickory Drive, Waltham, Massachusetts.
2. Respondent VISX is a corporation organized, existing, and doing business under and by virtue of the laws of Delaware with its office and principal place of business located at 3400 Central Expressway, Santa Clara, California.